Impact of autoantibody status on stratifying the risk of organ involvement and mortality in SSc: experience from a multicentre French cohort of 1605 patients.

Fiche publication

Date publication

novembre 2024

Journal

RMD open

Auteurs

Membres identifiés du Cancéropôle Est :
Pr JOLLY Damien , Pr MARTIN Thierry

Tous les auteurs :
Didier K, Sobanski V, Robbins A, Truchetet ME, Barnetche T, Contin-Bordes C, Hot A, Fort R, Guilpain P, Maria A, Agard C, Pennaforte JL, Viguier M, Martin T, Jolly D, Barbe C, Giusti D, Launay D, Servettaz A

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/39572073

Résumé

Systemic sclerosis (SSc) is a rare autoimmune disease currently classified into two subgroups based on skin extension. The aim of this study was to determine in a large cohort whether the determination of autoantibody (AAb) profile among a full antinuclear AAbs panel including nine specificities had a higher impact than skin phenotype on stratifying the risk of organ involvement and mortality in SSc.