Time-restricted feeding prevents memory impairments induced by obesogenic diet consumption, via hippocampal thyroid hormone signaling.

Fiche publication

Date publication

novembre 2024

Journal

Molecular metabolism

Auteurs

Membres identifiés du Cancéropôle Est :
Dr CIOCCA Dominique

Tous les auteurs :
Helbling JC, Ginieis R, Mortessagne P, Ruiz-Gayo M, Bakoyiannis I, Ducourneau EG, Ciocca D, Boulete IM, Favereaux A, Ces A, Montalban E, Capuron L, Jeanneteau F, Ferreira G, Challet E, Moisan MP

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/39515608

Résumé

The early consumption of calorie-rich diet disrupts circadian rhythms and has adverse effects on memory, yet the effects of time-restricted feeding (TRF) and the underlying molecular mechanisms are unknown. Here, we set out to identify the behavioral and molecular circadian rhythms disruptions generated by juvenile obesogenic diet consumption and their restoration by TRF in male mice.