Adaptation of antibiotics and antifungal strategy to preoperative biliary drainage to improve postoperative outcomes after pancreatic head resection.

Fiche publication

Date publication

décembre 2024

Journal

World journal of surgery

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PESSAUX Patrick

Tous les auteurs :
Giannone F, Lagarrigue C, Ligurgo O, Jazaerli L, Mertes PM, Collange O, Pessaux P

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/39681975

Résumé

Biliary contamination significantly correlates with major comorbidities during pancreatic head resection. Recently, a piperacillin-tazobactam prophylaxis demonstrated a lower rate of infectious complications (IC) and postoperative pancreatic fistula (POPF) in this population. However, bacterial contamination is rare in patients without a preoperative biliary drainage (PBD) and probably could not benefit from this antibiotic. Furthermore, little is known about the role of biliary fungal contamination.