Fiche publication
Date publication
décembre 2024
Journal
Frontiers in endocrinology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr SORG Tania
Tous les auteurs :
Springer M, Meugnier E, Schnabl K, Hof KS, Champy MF, Sorg T, Petit-Demoulière B, Germain N, Galusca B, Estour B, Vidal H, Klingenspor M, Hager J
Lien Pubmed
Résumé
Overweight and obesity affects millions of individuals worldwide and consequently represents a major public health concern. Individuals living with overweight and obesity have difficulty maintaining a low body weight due to known physiological mechanisms which prevent further weight loss and drive weight regain. In contrast, mechanisms which promote low body weight maintenance receive less attention and are largely unknown. To uncover these intrinsic mechanisms, we investigated a human cohort of constitutionally thin (CT) individuals which maintain a low body weight and are resistant to weight gain despite exposure to an obesogenic environment.
Mots clés
browning, leanness, obesity, sulfotransferase 1A1, white adipose tissue
Référence
Front Endocrinol (Lausanne). 2024 12 4;15:1448107
