Circulating growth differentiation factor-15 levels are associated with early echocardiographic signs of diastolic function impairment in the STANISLAS cohort: A 20-year follow-up study.

Fiche publication

Date publication

janvier 2025

Journal

European journal of heart failure

Auteurs

Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick

Tous les auteurs :
Monzo L, Xhaard C, Ferreira JP, Baudry G, Lamiral Z, Duarte K, Bozec E, Boivin JM, Huttin O, Rossignol P, Zannad F, Girerd N

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/39834240

Résumé

Early identification of healthy subjects prone to develop cardiac dysfunction may be instrumental to prevention strategies. Our study aimed to evaluate whether circulating levels of growth differentiation factor-15 (GDF-15) could predict adverse changes in echocardiographic indexes of cardiac structure and function in an initially healthy populational familial cohort with a long follow-up (STANISLAS cohort).