Influence of Anticoagulants on Platelet Counts: A Study and Recommendations From the French Speaking Cellular Hematology Group (GFHC).

Fiche publication

Date publication

janvier 2025

Journal

International journal of laboratory hematology

Auteurs

Membres identifiés du Cancéropôle Est :
Dr LESESVE Jean-François

Tous les auteurs :
Wuilleme S, Girard S, Soulard M, Chatelain B, Etienne E, Guiheneuf E, Geneviève F, Vedrenne A, Lesesve JF, Baccini V, Bardet V

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/39821603

Résumé

For complete blood count, ethylenediaminetetraacetic acid (EDTA) is universally used and has been recognized as the most robust anticoagulant. However, it may lead to pseudothrombocytopenia (PTCT), due to the formation of platelet clumps, which is currently followed by resampling on sodium citrate. Other possible anticoagulants are citrate theophylline adenosine dipyridamole (CTAD) and MgSO. These anticoagulants were compared here for resolution of PTCT and platelet count values and stability.