Fiche publication
Date publication
janvier 2025
Journal
Annales d'endocrinologie
Auteurs
Membres identifiés du Cancéropôle Est :
Pr VERGES Bruno
Tous les auteurs :
Scheyer N, Frey S, Koumakis E, Guérin C, Desailloud R, Groussin L, Cariou B, Vergès B, Brunaud L, Mirallié E, Figueres L, Lasolle H
Lien Pubmed
Résumé
At present, primary hyperparathyroidism is most often discovered in an asymptomatic patient, but can sometimes be revealed by a renal or bone complications. In all cases, a full work-up is recommended, with assessment of renal function (glomerular filtration rate), 24-hour calciuria, screening for risk factors for lithiasis, and renal and urinary tract imaging (ultrasound or CT scan) to look for stones or nephrocalcinosis. Bone densitometry, with measurements of the spine, femur and radius, is the recommended reference test for demineralization. Standard X-rays of the spine or other imaging techniques are recommended for the detection of asymptomatic vertebral fracture. Neurocognitive manifestations, reduced quality of life or cardiovascular manifestations should not be routinely screened for, as they are not currently consensual criteria for surgical indications.
Mots clés
Primary hyperparathyroidism, bone densitometry, hypercalciuria, nephrocalcinosis, osteoporosis, quality of life, renal failure, renal lithiasis, vertebral fracture
Référence
Ann Endocrinol (Paris). 2025 01 14;:101692