Using a Tailored Digital Health Intervention for Family Communication and Cascade Genetic Testing in Swiss and Korean Families With Hereditary Breast and Ovarian Cancer: Protocol for the DIALOGUE Study.

Date publication

juin 2021

Journal

JMIR research protocols

Auteurs

Membres identifiés du Cancéropôle Est :
Dr ACETI Monica

Tous les auteurs :
Kim S, Aceti M, Baroutsou V, Bürki N, Caiata-Zufferey M, Cattaneo M, Chappuis PO, Ciorba FM, Graffeo-Galbiati R, Heinzelmann-Schwarz V, Jeong J, Jung MM, Kim SW, Kim J, Lim MC, Ming C, Monnerat C, Park HS, Park SH, Pedrazzani CA, Rabaglio M, Ryu JM, Saccilotto R, Wieser S, Zürrer-Härdi U, Katapodi MC

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/34114954

Résumé

In hereditary breast and ovarian cancer (HBOC), family communication of genetic test results is essential for cascade genetic screening, that is, identifying and testing blood relatives of known mutation carriers to determine whether they also carry the pathogenic variant, and to propose preventive and clinical management options. However, up to 50% of blood relatives are unaware of relevant genetic information, suggesting that potential benefits of genetic testing are not communicated effectively within family networks. Technology can facilitate communication and genetic education within HBOC families.

Mots clés

HBOC, RE-AIM, communicating, coping, cultural and linguistic adaptation, decisional conflict, implementation, mobile phone, proportion of informed at-risk relatives

Référence

JMIR Res Protoc. 2021 06 11;10(6):e26264