Fiche publication
Date publication
février 2025
Journal
EBioMedicine
Auteurs
Membres identifiés du Cancéropôle Est :
Dr LUTZ Pierre-Eric
,
Dr YALCIN CHRISTMANN Ipek
Tous les auteurs :
Mokhtari A, Ibrahim EC, Gloaguen A, Barrot CC, Cohen D, Derouin M, Vachon H, Charbonnier G, Loriod B, Decraene C, Yalcin I, Marie-Claire C, Etain B, Belzeaux R, Delahaye-Duriez A, Lutz PE
Lien Pubmed
Résumé
Major depressive disorder (MDD) is a leading cause of disability, with a twofold increase in prevalence in women compared to men. Over the last few years, identifying molecular biomarkers of MDD has proven challenging, reflecting interactions among multiple environmental and genetic factors. Recently, epigenetic processes have been proposed as mediators of such interactions, with the potential for biomarker development.
Mots clés
DNA methylation, Depression, Multiomic integration, Sex differences, Transcriptomic, microRNA
Référence
EBioMedicine. 2025 02 5;113:105569
