Fiche publication
Date publication
janvier 2025
Journal
Healthcare (Basel, Switzerland)
Auteurs
Membres identifiés du Cancéropôle Est :
Dr FROCHOT Céline
Tous les auteurs :
Bezerra DT, Mesquita-Ferrari RA, Fernandes KPS, Bussadori SK, Motta LJ, Ando-Suguimoto ES, Frochot C, Perini AM, Rossi F, Mimica MJ, Pereira BJ, Horliana ACRT
Lien Pubmed
Résumé
Infection poses a significant threat of mortality in patients with chronic kidney disease (CKD) undergoing hemodialysis. () is a common etiological agent, with prior nasal colonization identified as a risk factor for infection. The aim of the present cross-sectional study was to determine the prevalence of nasal carriage among patients with CKD undergoing dialysis at a university hospital and identify potential factors associated with colonization. Nasal swabs were obtained, and bacterial isolates were identified using matrix-assisted laser desorption/ionization time-of-flight spectrometry and antibiogram testing with the Vitek 2 system. Demographic and clinical data were collected for the investigation of risk factors associated with colonization. Among the 96 patients analyzed, 34 were carriers of Among these carriers, three (8.8%) harbored oxacillin-resistant strains. More than half of the strains exhibited resistance to clindamycin but susceptibility to oxacillin. Colonization was associated with age and the use of corticosteroids/immunosuppressants. The prevalence of nasal carriage was high among patients undergoing dialysis at the university hospital, exceeding that found in the general population. Nasal colonization by was linked to corticosteroid use and age. Understanding factors associated with nasal colonization in patients on dialysis can assist healthcare providers in preventing the spread of infection and cross-contamination, while reducing risk in this population.
Mots clés
Staphylococcus aureus, chronic kidney disease, oxacillin-resistant strains
Référence
Healthcare (Basel). 2025 01 26;13(3):
