Fiche publication
Date publication
juillet 2015
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GIANGRANDE Angela
,
Dr CATTENOZ Pierre
Tous les auteurs :
Altenhein B, Cattenoz PB, Giangrande A
Lien Pubmed
Résumé
Throughout evolution, glia have key regulatory roles in neural development and function. Typically, they control the response to developmental and/or pathological signals, thereby affecting neural proliferation, remodeling, survival, and regeneration. Such complex biology depends on the plastic features of glial cells, but also on the presence of different classes of glial cells, hence the importance of understanding the cellular and the molecular mechanisms underlying their development. The fly community has made major breakthroughs by characterizing the bases of gliogenesis and here we describe the glial lineages as well as the glial promoting factor active in the embryo of Drosophila melanogaster. For further resources related to this article, please visit the WIREs website.
Référence
Wiley Interdiscip Rev Dev Biol. 2015 Jul 30
