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Date publication
février 2025
Journal
European journal of nuclear medicine and molecular imaging
Auteurs
Membres identifiés du Cancéropôle Est :
Dr CASASNOVAS Olivier
Tous les auteurs :
Malmon S, Casasnovas O, Fournier M, Cartron G, Kanoun S, Cottereau AS, Herbaux C, Al Tabaa Y
Lien Pubmed
Résumé
Total metabolic tumor volume (TMTV) at baseline becomes a key biomarker in several lymphoma subtypes. Variability in segmentation methods such as 41%SUVmax and SUVmax > 4 has limited its clinical application. Additionally, immune-checkpoint-inhibitors introduced challenges in response assessment due to pseudoprogression, complicating the use of traditional metrics. This study investigates the prognostic impact of baseline- and residual-TMTV and introduces a novel personalized-liver-based-threshold (pTMTV) to enhance precision in patient stratification.
Mots clés
Baseline TMTV, Lymphoma, PET/CT, Patient based segmentation method, Patient outcomes stratification, Residual TMTV
Référence
Eur J Nucl Med Mol Imaging. 2025 02 22;:
