Fiche publication
Date publication
mars 2025
Journal
Targeted oncology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr SCHOTT Roland
Tous les auteurs :
Mourlanette J, Rousseau-Bussac G, Mallah S, Guisier F, Zalcman G, Veillon R, Audigier-Valette C, Roa M, Nicolle I, Doubre H, Cloarec N, Lamy R, Morel H, Curcio H, Lagrange A, Schott R, Sabatini M, Toffart AC, Pinsolle J, Bennouna J, Chouaid C, Mazieres J
Lien Pubmed
Résumé
ROS1 chromosomic rearrangement is a rare oncogenic driver, and patients with this rearrangement benefit from specific targeted treatments in the first-line setting. However, therapeutic options are limited in pretreated patients. Brigatinib is a validated drug for ALK rearrangements, and also has an in vitro activity against ROS1. In vivo efficacy is also suggested in some clinical series.
Référence
Target Oncol. 2025 03 13;:
