Fiche publication
Date publication
mars 2025
Journal
RMD open
Auteurs
Membres identifiés du Cancéropôle Est :
Dr METZGER Daniel
,
Dr LAVERNY Gilles
,
Mme MESSADDEQ Nadia
,
Dr OULAD-ABDELGHANI Mustapha
,
Pr GENY Bernard
Tous les auteurs :
Giannini M, Rovito D, Oulad-Abdelghani M, Messaddeq N, Debrut L, Quiring G, Kessler P, Charles AL, Geny B, Metzger D, Laverny G, Meyer A
Lien Pubmed
Résumé
Inflammatory myopathies (IM) are a group of severe autoimmune diseases, sharing some similarities, whose cause is unknown and treatment is empirical.While C-protein-induced myositis (CIM), the most currently used mouse model of IM, has removed some roadblocks to understand and improve the treatment of IM, it has only been partially characterised and its generation limited by poor reproducibility. This study aimed at optimising the generation and the characterisation of CIM.
Mots clés
Autoimmune Diseases, Dermatomyositis, Inflammation, Polymyositis
Référence
RMD Open. 2025 03 5;11(1):
