Fiche publication
Date publication
janvier 2017
Journal
Sensors (Basel, Switzerland)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr LESNIEWSKA Eric
,
Dr BOURILLOT Eric
Tous les auteurs :
Ionescu RE, Aybeke EN, Bourillot E, Lacroute Y, Lesniewska E, Adam PM, Bijeon JL
Lien Pubmed
Résumé
Metallic nanoparticles are considered as active supports in the development of specific chemical or biological biosensors. Well-organized nanoparticles can be prepared either through expensive (e.g., electron beam lithography) or inexpensive (e.g., thermal synthesis) approaches where different shapes of nanoparticles are easily obtained over large solid surfaces. Herein, the authors propose a low-cost thermal synthesis of active plasmonic nanostructures on thin gold layers modified glass supports after 1 h holding on a hot plate (~350 °C). The resulted annealed nanoparticles proved a good reproducibility of localized surface plasmon resonance (LSPR) and surface enhanced Raman spectroscopy (SERS) optical responses and where used for the detection of low concentrations of two model (bio)chemical molecules, namely the human cytochrome b5 (Cyt-b5) and -1,2-bis(4-pyridyl)ethylene (BPE).
Mots clés
(bio)functionalization, annealed gold nanostructures, human cytochrome b5, improved LSPR and SERS sensitivity, trans-1,2-bis(4-pyridyl)ethylene
Référence
Sensors (Basel). 2017 01 26;17(2):
