Fiche publication
Date publication
avril 2025
Journal
Communications biology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MOULIN Thierry
Tous les auteurs :
Lesourd M, Osiurak F, Martin J, Hague S, Laroze M, Clément G, Medeiros de Bustos E, Fargeix G, Magnin E, Moulin T
Lien Pubmed
Résumé
Action tool knowledge can be assessed mainly with two kinds of tasks: tool-tool and hand-tool compatibility tasks. While these tasks are used to assess action tool knowledge, recent data showed striking dissociations between these tasks in brain-damaged patients. In this study, we explored the neuropsychological dissociations (Experiment 1; 60 brain-damaged patients) and the potential cognitive mechanisms engaged during these two tasks (Experiment 2; 52 healthy participants). Finally, we also reanalyzed fMRI data to investigate the neural bases engaged in tool-tool and hand-tool compatibility tasks (Experiment 3; 34 healthy participants). The three experiments provide convergent arguments by showing that both tasks share common core computations supported by a left-lateralized brain network, but hand-tool compatibility task engages regions outside of this brain network and is explained by visual imagery while tool-tool task is rather explained by motor imagery. Our results shed a new light on action tool knowledge tasks.
Mots clés
Humans, Male, Female, Adult, Magnetic Resonance Imaging, Cognition, physiology, Middle Aged, Hand, physiology, Brain, physiology, Young Adult, Psychomotor Performance, physiology, Brain Mapping
Référence
Commun Biol. 2025 04 3;8(1):552
