PET-based response assessment criteria for diffuse gliomas (PET RANO 1.0): methodological application in [F]-FDOPA PET imaging.

Fiche publication

Date publication

avril 2025

Journal

EJNMMI research

Auteurs

Membres identifiés du Cancéropôle Est :
Pr TAILLANDIER Luc , Pr VERGER Antoine

Tous les auteurs :
Stien G, Zinsz A, Ahrari S, Taillandier L, Blonski M, Imbert L, Zaragori T, Verger A

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/40251407

Résumé

The Response Assessment in Neuro-Oncology (RANO) group recently reported PET-based response assessment criteria for diffuse gliomas (PET RANO 1.0). The objective of this study was to evaluate the methodological application of these criteria for the amino acid [F]-FDOPA radiotracer. Patients with confirmed glioma who underwent at least one baseline [F]-FDOPA PET scan were retrospectively included. The PET RANO 1.0 criteria were evaluated regarding their methodological application. Patients with at least one follow-up PET scan were evaluated with the PET RANO 1.0 criteria as compared to the routine interpretation of two experts not using the PET RANO 1.0 criteria, defined as the reference. The different PET parameters included in the PET RANO 1.0 criteria were evaluated separately regarding their contribution.