Total plasma protein in very preterm babies: prognostic value and comparison with illness severity scores.

Date publication

janvier 2013

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BINQUET Christine , Pr QUANTIN Catherine

Tous les auteurs :
Iacobelli S, Bonsante F, Quantin C, Robillard PY, Binquet C, Gouyon JB

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/23614036

Résumé

OBJECTIVE: We aimed to investigate the predictive value for severe adverse outcome of plasma protein measurements on day one of life in very preterm infants and to compare total plasma protein levels with the validated illness severity scores CRIB, CRIB-II, SNAP-II and SNAPPE-II, regarding their predictive ability for severe adverse outcome. METHODS: We analyzed a cohort of infants born at 24-31 weeks gestation, admitted to the tertiary intensive care unit of a university hospital over 10.5 years. The outcome measure was "severe adverse outcome" defined as death before discharge or severe neurological injury on cranial ultrasound. The adjusted odd ratio (aOR) and 95% confidence interval (95% CI) of severe adverse outcome for hypoproteinemia (total plasma protein level

Référence

PLoS One. 2013 Apr 16;8(4):e62210