[Prenatal diethylstilbestrol exposure and breast cancer].

Date publication

décembre 2012

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MATHELIN Carole

Tous les auteurs :
Frigo S, Malina C, Mathelin C

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/23102737

Résumé

Diethylstilbestrol (DES) is a synthetic estrogen prescribed to prevent miscarriages until 1977. Its role in the development of vaginal adenocarcinoma and cervical dysplasia is known and screening codified. Recent cohort studies show that exposure to DES in utero increases breast cancer risk especially after 40 years. This article reports the observation of a breast cancer of exceptional gravity in a patient exposed to DES in utero. It details the risk of breast cancer for "DES daughters" and support possible screening modalities.

Référence

Gynecol Obstet Fertil. 2012 Dec;40(12):784-6