Are postoperative consequences of neoadjuvant chemotherapy for non-small cell lung cancer more severe in elderly patients?

Date publication

mai 2012

Auteurs

Membres identifiés du Cancéropôle Est :
Pr BERNARD Alain , Pr FALCOZ Pierre-Emmanuel

Tous les auteurs :
Rivera C, Jougon J, Dahan M, Falcoz PE, Bernard A, Brouchet L

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/22078278

Résumé

OBJECTIVES: The purpose of this study was to assess the postoperative morbidity of patients >/=75 years with non-small cell lung cancer (NSCLC) who underwent neoadjuvant chemotherapy, comparing them to younger patients. METHODS: We performed a case-control study over a 5-year period using Epithor, the French Society of Thoracic and Cardiovascular Surgery database, including to date more than 160,000 procedures from 103 institutions. We collected prospectively the data concerning 1510 patients with NSCLC who underwent preoperative chemotherapy, from January 2005 to December 2009. In order to compare patients with similar characteristics, we matched the 81 patients >/=75 to 81 controls (

Référence

Lung Cancer. 2012 May;76(2):216-21