Extended benefit from sequential administration of docetaxel after standard fluorouracil, epirubicin, and cyclophosphamide regimen for node-positive breast cancer: the 8-year follow-up results of the UNICANCER-PACS01 trial.

Date publication

janvier 2012

Auteurs

Membres identifiés du Cancéropôle Est :
Dr COUDERT Bruno , Dr EYMARD Jean-Christophe , Pr PETIT Thierry

Tous les auteurs :
Coudert B, Asselain B, Campone M, Spielmann M, Machiels JP, Penault-Llorca F, Serin D, Levy C, Romieu G, Canon JL, Orfeuvre H, Piot G, Petit T, Jerusalem G, Audhuy B, Veyret C, Beauduin M, Eymard JC, Martin AL, Roche H

Lien Pubmed

https://www.ncbi.nlm.nih.gov/pubmed/22610153

Résumé

PURPOSE: The initial report from the Programme Action Concertee Sein (PACS) PACS01 trial demonstrated a benefit at 5 years for disease-free survival (DFS) and overall survival (OS) rates with the sequential administration of docetaxel after FEC100 (fluorouracil 500 mg/m(2), epirubicin 100 mg/m(2), and cyclophosphamide 500 mg/m(2)) for patients with node-positive, operable breast cancer. We evaluate here the impact of this regimen at 8 years. PATIENTS AND METHODS: Between June 1997 and March 2000, a total of 1,999 patients (age

Référence

Oncologist. 2012;17(7):900-9