Fiche publication
Date publication
mai 2015
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BEDENNE Laurent
,
Pr BINQUET Christine
,
Dr BOUVIER Anne-Marie
,
Dr FOURNEL Isabelle
,
Dr JOOSTE Valérie
Tous les auteurs :
Frerot M, Jooste V, Binquet C, Fournel I, Bedenne L, Bouvier AM
Lien Pubmed
Résumé
BACKGROUND: Inclusion in a randomized therapeutic trial represents an optimal therapeutic strategy. AIMS: To determine the influence of demographic characteristics and deprivation on the enrolment of patients in digestive cancer clinical trials. METHODS: Between 2004 and 2010, 4632 patients were recorded by the Burgundy Digestive Cancer Registry. According to a balancing score, the 136 patients included in a clinical trial were matched with 272 patients who met the eligibility criteria for trials. Deprivation was measured by the ecological European deprivation index. A conditional multivariate logistic regression was performed. RESULTS: Patients aged over 75 years were significantly less likely to be included in clinical trials than younger patients (odds ratio 0.33; [0.13-0.87]). Patients treated in private institutions were also less likely to be enrolled than those treated in public institutions (odds ratio 0.04; [0.01-0.16]; p
Référence
Dig Liver Dis. 2015 May 28. pii: S1590-8658(15)00346-1
