Fiche publication
Date publication
août 2011
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GUILLEMIN Francis
Tous les auteurs :
Guillemin F, Iversen MD, Rat AC, Osborne R, Petersson IF
Lien Pubmed
Résumé
INTRODUCTION: Nonpharmacologic interventions are themselves complex and are often combined with drugs and other interventions in the treatment of rheumatic diseases. Therefore, overall strategies for treatment are complex interventions. These should be evaluated regarding their processes and outcomes. METHODS: The CARE network, an international organization of health professionals (physicians and nonphysicians) and patients conducted a survey in 2008 to identify core outcomes in the ICF perspective, completed with a second survey (2009-2010) with patients in routine practice. These surveys have provided new information about domains to investigate as a basis for evaluating complex interventions. RESULTS: Outcome Measures in Rheumatology Clinical Trials (OMERACT) participants in this Special Interest Group agreed that current outcomes used in pharmacological research are not sufficient if the nonpharmacologic independent or combined contributions are to be assessed; other domains need to be addressed. This is an area of interest for further development. CONCLUSION: Recommendations are proposed to develop research in the area of outcome for evaluation of complex interventions in rheumatic diseases.
Référence
J Rheumatol. 2011 Aug;38(8):1803-5.
