Fiche publication
Date publication
juillet 2011
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BERNIER-CHASTAGNER Valérie
Tous les auteurs :
Spasic E, Buchheit I, Bernier V, Noel A
Lien Pubmed
Résumé
PURPOSE: To compare several techniques in order to determine the best treatment for benign brain tumours. METHODS AND PATIENTS: A retrospective study was performed for five patients who received 3D-conformal radiotherapy, intensity modulated radiotherapy or CyberKnife((R)). These patients had a meningioma, a pituitary tumour, a craniopharyngioma or a neurinoma. In each case, these treatment plans were optimised and compared with the three other dosimetries. Radiobiological or positioning parameters were evaluated, as well as dosimetric parameters, in order to compare treatments with different characteristics. RESULTS: The dosimetric parameters showed that the choice of treatment seemed to be determined mostly by tumour size, shape and proximity with organs at risk (not tumour localisation). Whereas the results showed no significant deviations with regards to the radiobiological parameters. Therefore, with these parameters, it was difficult to give priority to a treatment. CONCLUSIONS: With regards to benign brain tumours of medium or large size, intensity modulated radiotherapy seemed the recommended treatment. It enabled to obtain a good ratio between efficacy and toxicity for tumours that are really close to organs at risk. Concerning small benign brain tumours, the CyberKnife((R)) was probably the best treatment.
Référence
Cancer Radiother. 2011 Jul;15(4):287-93
