Fiche publication
Date publication
septembre 2010
Auteurs
Membres identifiés du Cancéropôle Est :
Pr RAMANAH Rajeev
Tous les auteurs :
Ramanah R, Mairot J, Clement MC, Parratte B, Maillet R, Riethmuller D
Lien Pubmed
Résumé
INTRODUCTION AND HYPOTHESIS: The aim was to assess the efficacy of three-compartment pelvic organ prolapse (POP) vaginal repair using the InteXen biocompatible porcine dermal graft as compared to traditional colporrhaphy with sacrospinous ligament suspension. METHODS: Preoperative, operative, postoperative and follow-up data were collected retrospectively. Objective recurrence was defined as POP quantification >or= stage II and subjective recurrence as a symptomatic bulge. RESULTS: Each group consisted of 63 patients. Surgery time was longer using InteXen (72 +/- 24.5 vs 55 +/- 23.5 min, p = 0.0002). Length of hospital stay (4.6 +/- 1.6 vs 4.9 +/- 2.1 days, p = 0.34) as well as duration of follow-up (37.1 vs 35.7 months, p = 0.45) were equivalent between the two groups. No case of mesh erosion or infection was noted. The objective (17% vs 8%, p = 0.12) and subjective recurrence rates (13% vs 5%, p = 0.12) between the two groups were not statistically different. CONCLUSIONS: InteXen was well tolerated but had similar efficacy to traditional colporrhaphy and sacrospinous ligament suspension.
Référence
Int Urogynecol J Pelvic Floor Dysfunct. 2010 Sep;21(9):1151-6
