Fiche personne
Coordonnées
Laboratoire d'anatomie pathologique
Hôpital de Hautepierre
1 avenue Molière
67098 STRASBOURG Cedex
03 88 12 84 41
Territoire
Alsace
Statut
Hospitalo-Universitaire
Affiliation
Hôpitaux universitaires de Strasbourg (CHRU Strasbourg)
Université de Strasbourg (Unistra)
Laboratoire de bioimagerie et pathologies UMR CNRS 7021 (LBP)
Équipes/plateformes
Equipe UMR 7021 - Equipe "Oncologie translationnelle, transversale et thérapeutique - OnKO3T"
Recherche
Expertises :
- Clinique:Anatomo-pathologie
Publications
CIC/ATXN1-rearranged tumors in the central nervous system are mainly represented by sarcomas: A comprehensive clinicopathological and epigenetic series.
Tauziède-Espariat A, Ebrahimi A, Boddaert N, Pietsch T, Grajkowska W, Blau T, Koch A, Sievers P, Guillemot D, Pierron G, Uro-Coste E, Nicaise Y, Siegfried A, Gilles A, Bielle F, Mokhtari K, Cazals-Hatem D, Iakovlev G, Lhermitte B, Entz-Werle N, Csanyi M, Maurage CA, Legrand V, Boutonnat J, Godfraind C, McLeer A, Hasty L, Métais A, Aboubakr O, Blauwblomme T, Beccaria K, Dangouloff-Ros V, Varlet P,
Brain Pathol. 2024 10 23;:e13303
Fulminant leptomeningeal disease diagnosed as comutant H3F3A and FGFR diffuse midline glioma.
Benistant L, Reita D, Schenck M, Castelain V, Cebula H, Lhermitte B, Bender L
Ann Clin Transl Neurol. 2024 10 23;:
Clinical impact of large genomic explorations at diagnosis in 198 pediatric solid tumors: a monocentric study aiming practical feasibility of precision oncology.
Simon J, Reita D, Guerin E, Lhermitte B, Weingertner N, Lefebvre F, Karanian M, Masliah-Planchon J, Lindner V, Onea A, Jannier S, Salmon A, Bergthold G, Vincent F, Deschuyter M, Barbaza MO, Entz-Werlé N
BMC Cancer. 2024 10 21;24(1):1296
[Cerebromeningeal amyloid angiopathy].
Wolf T, Chammas A, Lannes B, Lhermitte B
Ann Pathol. 2024 10 1;:
Radiotherapy for central neurocytoma: A multicentric retrospective study in France.
Virbel G, Mallereau CH, Lhermitte B, Feuvret L, Biau J, Clément L, Khoury C, Bernier V, Milhade N, Tanguy R, Colin P, Cébula H, Proust F, Bauchet L, Noël G
Cancer Radiother. 2024 08 1;:
Sclerosing epithelioid fibrosarcoma: a new mesenchymal non-meningothelial tumor involving the central nervous system?
Wolf T, Sinnes V, Reita D, Chammas A, Gantzer J, Weingertner N, Chenard MP, Todeschi J, Salmanli C, Deschuyter M, Noel G, Entz-Werle N, Lhermitte B
Virchows Arch. 2024 06 20;:
Central nervous system siderosis associated with multiple cerebral aneurysms: literature review and description of an additional case.
Dembour V, Mallereau CH, Chibbaro S, Segbedji FKK, Pop R, Cebula H, Lhermitte B, Todeschi J
World Neurosurg. 2024 05 18;:
CNS tumors with PLAGL1-fusion: beyond ZFTA and YAP1 in the genetic spectrum of supratentorial ependymomas.
Tauziède-Espariat A, Nicaise Y, Sievers P, Sahm F, von Deimling A, Guillemot D, Pierron G, Duchesne M, Edjlali M, Dangouloff-Ros V, Boddaert N, Roux A, Dezamis E, Hasty L, Lhermitte B, Hirsch E, Hirsch MPV, Ardellier FD, Karnoub MA, Csanyi M, Maurage CA, Mokhtari K, Bielle F, Rigau V, Roujeau T, Abad M, Klein S, Bernier M, Horodyckid C, Adam C, Brandal P, Niehusmann P, Vannod-Michel Q, Provost C, de Champfleur NM, Nichelli L, Métais A, Mariet C, Chrétien F, Blauwblomme T, Beccaria K, Pallud J, Puget S, Uro-Coste E, Varlet P,
Acta Neuropathol Commun. 2024 04 5;12(1):55
Coxal giant cell-rich tumour harbouring an NUTM1 gene fusion: a new molecular subtype of giant cell tumour of bone?
Fattori A, Reita D, Brinkert D, Willaume T, Gantzer J, Karanian M, Lhermitte B, Wolf T, De Pinieux G, Weingertner N
Histopathology. 2024 01 16;:
Second Cancer affecting the Central Nervous System: Systematic Literature Review Exploring the Link between Malignant Melanoma and Glioblastoma.
Todeschi J, Dannhoff G, Chibbaro S, Segbedji F, Spatola G, Mallereau CH, Noel G, Schott R, Lhermitte B, Cebula H, Ganau M
World Neurosurg. 2023 08 23;:
Genomic profiling of a metastatic anaplastic melanocytic neuroectodermal tumor arising from a mature thymic teratoma as part of a mediastinal germ cell tumor.
Mayeur S, Lhermitte B, Gantzer J, Molitor A, Stemmelen T, Meyer S, Kolmer A, Kurtz JE, Bahram S, Carapito R
Cold Spring Harb Mol Case Stud. 2023 04;9(2):
CNS neuroblastoma, FOXR2-activated and its mimics: a relevant panel approach for work-up and accurate diagnosis of this rare neoplasm.
Tauziède-Espariat A, Figarella-Branger D, Métais A, Uro-Coste E, Maurage CA, Lhermitte B, Aline-Fardin A, Hasty L, Vasiljevic A, Chiforeanu D, Chotard G, Adle-Biassette H, Meurgey A, Saffroy R, Guillemot D, Pierron G, Sievers P, Varlet P,
Acta Neuropathol Commun. 2023 03 14;11(1):43
p16 Immunohistochemical Expression as a Surrogate Assessment of CDKN2A Alteration in Gliomas Leading to Prognostic Significances.
Geyer L, Wolf T, Chenard MP, Cebula H, Schott R, Noel G, Guerin E, Pencreach E, Reita D, Entz-Werlé N, Lhermitte B
Cancers (Basel). 2023 02 28;15(5):
Molecular Heterogeneity in BRAF-Mutant Gliomas: Diagnostic, Prognostic, and Therapeutic Implications.
Lhermitte B, Wolf T, Chenard MP, Coca A, Todeschi J, Proust F, Hirsch E, Schott R, Noel G, Guerin E, Reita D, Chammas A, Salmon A, Martin S, Dontenwill M, Entz-Werlé N
Cancers (Basel). 2023 02 16;15(4):
Bioimaging Nucleic-Acid Aptamers with Different Specificities in Human Glioblastoma Tissues Highlights Tumoral Heterogeneity.
Cruz Da Silva E, Foppolo S, Lhermitte B, Ingremeau M, Justiniano H, Klein L, Chenard MP, Vauchelles R, Abdallah B, Lehmann M, Etienne-Selloum N, Dontenwill M, Choulier L
Pharmaceutics. 2022 09 20;14(10):
Engineering Novel 3D Models to Recreate High-Grade Osteosarcoma and its Immune and Extracellular Matrix Microenvironment.
Pierrevelcin M, Flacher V, Mueller CG, Vauchelles R, Guerin E, Lhermitte B, Pencreach E, Reisch A, Muller Q, Doumard L, Boufenghour W, Klymchenko AS, Foppolo S, Nazon C, Weingertner N, Martin S, Briandet C, Laithier V, Di Marco A, Bund L, Obrecht A, Villa P, Dontenwill M, Entz-Werlé N
Adv Healthc Mater. 2022 09 4;:e2200195
[Impact of NGS results on patient outcome with a multiform glioblastoma].
Rom M, Schott R, Pencreac'h E, Cébula H, Cox D, Bender L, Antoni D, Lhermitte B, Noel G
Cancer Radiother. 2022 06 14;:
Early-onset leukoencephalomyelopathy due to a biallelic NDUFV1 variant in a mid-forties patient.
Gschwind M, Garcia Segarra N, Schaller A, Bolognini R, Nuoffer JM, Hourez R, Deprez M, Lhermitte B, Maeder P, Tran C, Kuntzer T
Ann Clin Transl Neurol. 2022 Apr 28;:
Retrospective and integrative analyses of molecular characteristics and their specific imaging parameters in pediatric grade 1 gliomas.
Coutant M, Lhermitte B, Guérin E, Chammas A, Reita D, Sebastia C, Douzal V, Gabor F, Salmon A, Chenard MP, Todeschi J, Coca A, Heng MA, Vincent F, Entz-Werlé N
Pediatr Blood Cancer. 2022 Apr 4;:e29575
Rosette-forming glioneuronal tumours are midline, FGFR1-mutated tumours.
Appay R, Bielle F, Sievers P, Barets D, Fina F, Boutonnat J, Clovis A, Gauchotte G, Godfraind C, Lhermitte B, Maurage CA, Meyronet D, Mokhtari K, Rousseau A, Tauziède-Espariat A, Tortel MC, Uro-Coste E, Burel-Vandenbos F, Chotard G, Pesce F, Varlet P, Colin C, Figarella-Branger D
Neuropathol Appl Neurobiol. 2022 Mar 16;:e12813
Together Intra-Tumor Hypoxia and Macrophagic Immunity Are Driven Worst Outcome in Pediatric High-Grade Osteosarcomas.
Nazon C, Pierrevelcin M, Willaume T, Lhermitte B, Weingertner N, Marco AD, Bund L, Vincent F, Bierry G, Gomez-Brouchet A, Redini F, Gaspar N, Dontenwill M, Entz-Werle N
Cancers (Basel). 2022 Mar 14;14(6):
Interventional Magnetic-Resonance-Guided Cryotherapy Combined with Microsurgery for Recurrent Glioblastoma: An Innovative Treatment?
Cebula H, Garnon J, Todeschi J, Noel G, Lhermitte B, Mallereau CH, Chibbaro S, Burckel H, Schott R, Mathelin M, Gangi A, Proust F
Neurochirurgie. 2021 Dec 11;:
A Homozygous Missense Variant in PPP1R1B/DARPP-32 Is Associated With Generalized Complex Dystonia.
Khan A, Molitor A, Mayeur S, Zhang G, Rinaldi B, Lannes B, Lhermitte B, Umair M, Arold ST, Friant S, Rastegar S, Anheim M, Bahram S, Carapito R
Mov Disord. 2021 Nov 24;:
Co-culture of Glutamatergic Neurons and Pediatric High-Grade Glioma Cells Into Microfluidic Devices to Assess Electrical Interactions.
Fuchs Q, Batut A, Gleyzes M, Rontard J, Miny L, Libralato M, Vieira J, Debis D, Larramendy F, Honegger T, Messe M, Pierrevelcin M, Lhermitte B, Dontenwill M, Entz-Werlé N
J Vis Exp. 2021 Nov 17;(177):
[Histopathological diagnosis of an intoxication].
Fattori A, Arfeuille G, Parratte T, Gantzer J, Olagne J, Lannes B, Lhermitte B
Ann Pathol. 2021 Sep 2;:
Cerebral mucormycosis: neuroimaging findings and histopathological correlation.
Lersy F, Royer-Leblond J, Lhermitte B, Chammas A, Schneider F, Hansmann Y, Lefebvre N, Denis J, Sabou M, Lafitte F, Cotton F, Boncoeur-Martel MP, Tourdias T, Pruvo JP, Cottier JP, Herbrecht R, Kremer S
J Neurol. 2021 Jul 8;:
A DNA Repair and Cell Cycle Gene Expression Signature in Pediatric High-Grade Gliomas: Prognostic and Therapeutic Value.
Entz-Werlé N, Poidevin L, Nazarov PV, Poch O, Lhermitte B, Chenard MP, Burckel H, Guérin E, Fuchs Q, Castel D, Noel G, Choulier L, Dontenwill M, Van Dyck E
Cancers (Basel). 2021 May 7;13(9):
High risk of recurrence for grade II meningioma: a 10-year multicenter analysis of prognosis factors.
Bender L, Somme F, Lhermitte B, Ahle G, Boone M, Blonski M, Pouget C, Truc G, Cebula H, Noël G
Chin Clin Oncol. 2021 Mar 10;:
Biallelic RFC1-expansion in a French multicentric sporadic ataxia cohort.
Montaut S, Diedhiou N, Fahrer P, Marelli C, Lhermitte B, Robelin L, Vincent MC, Corti L, Taieb G, Gebus O, Rudolf G, Tarabeux J, Dondaine N, Canuet M, Almeras M, Benkirane M, Larrieu L, Chanson JB, Nadaj-Pakleza A, Echaniz-Laguna A, Cauquil C, Lannes B, Chelly J, Anheim M, Puccio H, Tranchant C
J Neurol. 2021 Mar 5;:
Pseudoprogression versus true progression in glioblastoma patients: a multiapproach literature review: Part 1 - Molecular, Morphological and Clinical features.
Le Fèvre C, Lhermitte B, Ahle G, Chambrelant I, Cebula H, Antoni D, Kelle Zr A, Schott R, Thiery A, Noël G
Crit Rev Oncol Hematol. 2020 Dec 8;:103188
SFCE-RAPIRI Phase I Study of Rapamycin Plus Irinotecan: A New Way to Target Intra-Tumor Hypoxia in Pediatric Refractory Cancers.
Jannier S, Kemmel V, Sebastia Sancho C, Chammas A, Sabo AN, Pencreach E, Farace F, Chenard MP, Lhermitte B, Geoerger B, Aerts I, Frappaz D, Leblond P, André N, Ducassou S, Corradini N, Bertozzi AI, Guérin E, Vincent F, Velten M, Entz-Werle N
Cancers (Basel). 2020 Oct 20;12(10):
Focus on Hypoxia-Related Pathways in Pediatric Osteosarcomas and Their Druggability.
Pierrevelcin M, Fuchs Q, Lhermitte B, Messé M, Guérin E, Weingertner N, Martin S, Lelong-Rebel I, Nazon C, Dontenwill M, Entz-Werlé N
Cells. 2020 Aug 31;9(9):
[Choice optimisation of radiation therapy technique for central neurocytomas from literature data].
Virbel G, Cebula H, Coca A, Lhermitte B, Bauchet L, Noël G
Cancer Radiother. 2020 Aug 1;:
Hypoxia Inducible Factors' Signaling in Pediatric High-Grade Gliomas: Role, Modelization and Innovative Targeted Approaches.
Fuchs Q, Pierrevelcin M, Messe M, Lhermitte B, Blandin AF, Papin C, Coca A, Dontenwill M, Entz-Werlé N
Cancers (Basel). 2020 Apr 15;12(4):
Primary Brain Rhabdomyosarcoma Causing Extracranial Metastases. Case Report with Narrative Review of Atypical Presentations and Their Diagnostic Challenges.
Mallereau CH, Ganau M, Todeschi J, Cebula H, Santin MD, Virbel G, Pop R, Lhermitte B, Proust F, Chibbaro S
World Neurosurg. 2020 Mar 27;:
Hypoxic Environment and Paired Hierarchical 3D and 2D Models of Pediatric -Mutated Gliomas Recreate the Patient Tumor Complexity.
Blandin AF, Durand A, Litzler M, Tripp A, Guérin É, Ruhland E, Obrecht A, Keime C, Fuchs Q, Reita D, Lhermitte B, Coca A, Jones C, Rebel IL, Villa P, Namer IJ, Dontenwill M, Guenot D, Entz-Werle N
Cancers (Basel). 2019 Nov 26;11(12):
Tumefactive inflammatory leukoencephalopathy in cocaine users: Report of three cases.
Pessini LM, Kremer S, Auger C, Castilló J, Pottecher J, de Sèze J, Lhermitte B, Maciag E, Rovira A
Mult Scler Relat Disord. 2019 Nov 4;38:101496
DIAGNOSTIC VALUE OF FUSION OF METABOLIC AND STRUCTURAL IMAGES FOR STEREOTACTIC BIOPSY OF BRAIN TUMORS WITHOUT ENHANCEMENT AFTER CONTRAST MEDIUM INJECTION.
Todeschi J, Bund C, Cebula H, Chibbaro S, Lhermitte B, Pin Y, Lefebvre F, Izzie JN, Proust F
Neurochirurgie. 2019 Sep 24;:
What Does Reduced FDG Uptake Mean in High-Grade Gliomas?
Bund C, Lhermitte B, Cicek AE, Ruhland E, Proust F, Namer IJ
Clin Nucl Med. 2019 Sep 12;:
Interleukin-32 Contributes to Human Nonalcoholic Fatty Liver Disease and Insulin Resistance.
Dali-Youcef N, Vix M, Costantino F, El-Saghire H, Lhermitte B, Callari C, D'Agostino J, Perretta S, Paveliu S, Gualtierotti M, Dumeny E, Oudot MA, Jaulin A, Dembélé D, Zeisel MB, Tomasetto C, Baumert TF, Doffoël M
Hepatol Commun. 2019 Sep;3(9):1205-1220
Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1.
Sievers P, Appay R, Schrimpf D, Stichel D, Reuss DE, Wefers AK, Reinhardt A, Coras R, Ruf VC, Schmid S, de Stricker K, Boldt HB, Kristensen BW, Petersen JK, Ulhøi BP, Gardberg M, Aronica E, Hasselblatt M, Brück W, Bielle F, Mokhtari K, Lhermitte B, Wick W, Herold-Mende C, Hänggi D, Brandner S, Giangaspero F, Capper D, Rushing E, Wesseling P, Pfister SM, Figarella-Branger D, von Deimling A, Sahm F, Jones DTW
Acta Neuropathol.. 2019 Jun 27;:
Can histologically normal epileptogenic zone share common electrophysiological phenotypes with focal cortical dysplasia? SEEG-based study in MRI-negative epileptic patients.
Lagarde S, Scholly J, Popa I, Valenti-Hirsch MP, Trebuchon A, McGonigal A, Milh M, Staack AM, Lannes B, Lhermitte B, Proust F, Benmekhbi M, Scavarda D, Carron R, Figarella-Branger D, Hirsch E, Bartolomei F
J. Neurol.. 2019 May 4;:
An integrated genomic and metabolomic approach for defining survival time in adult oligodendrogliomas patients.
Bund C, Guergova-Kuras M, Cicek AE, Moussallieh FM, Dali-Youcef N, Piotto M, Schneider P, Heller R, Entz-Werle N, Lhermitte B, Chenard MP, Schott R, Proust F, Noël G, Namer IJ
Metabolomics. 2019 Apr 29;15(5):69
Pathologic and MRI analysis in acute atypical inflammatory demyelinating lesions.
Ayrignac X, Rigau V, Lhermitte B, Vincent T, de Champfleur NM, Carra-Dalliere C, Charif M, Collongues N, de Seze J, Hebbadj S, Ahle G, Oesterlé H, Cotton F, Durand-Dubief F, Marignier R, Vukusic S, Taithe F, Cohen M, Guennoc AM, Kerbrat A, Edan G, Carsin-Nicol B, Allou T, Sablot D, Thouvenot E, Ruet A, Magy L, Boncoeur-Martel MP, Labauge P, Kremer S
J. Neurol.. 2019 Apr 23;:
Grade III meningioma with gastro-intestinal tract and brain metastases: case report and review of the literature.
Bender L, Lhermitte B, Carinato H, Baloglu S, Helali M, Cebula H, Antoni D, Noel G
World J Surg Oncol. 2019 Apr 16;17(1):70
Intracranial Solitary Fibrous Tumors: a heterogeneous entity with an uncertain clinical behavior.
Gubian A, Ganau M, Cebula H, Todeschi J, Scibilia N, Noel G, Spatola G, Chaussemy D, Nannavecchia B, P G, Coca A, Pop R, Signorelli F, Proust F, Lhermitte B, Chibbaro S
World Neurosurg. 2019 Feb 1;:
Multidisciplinary management of an intra-sellar cavernous hemangioma: Case report and review of the literature.
Chibbaro S, Cebula H, Ganau M, Gubian A, Todeschi J, Lhermitte B, Proust F, Noel G
J Clin Neurosci. 2018 Apr 2;:
FDG PET and MRI Findings in a Case of Bing-Neel Syndrome.
Bund C, Lhermitte B, De Seze J, Kremer S, Namer IJ
Clin Nucl Med. 2018 Apr;43(4):262-264
Metabolomic characterization of human hippocampus from drug-resistant epilepsy with mesial temporal seizure.
Detour J, Bund C, Behr C, Cebula H, Cicek EA, Valenti-Hirsch MP, Lannes B, Lhermitte B, Nehlig A, Kehrli P, Proust F, Hirsch E, Namer IJ
Epilepsia. 2018 Mar;59(3):607-616
Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1a axis inhibition.
Nguyen A, Moussallieh FM, Mackay A, Cicek AE, Coca A, Pierre Chenard M, Weingertner N, Lhermitte B, Letouzé E, Guérin E, Pencreach E, Jannier S, Guenot D, Jacques Namer I, Jones C, Entz-Werlé N
Oncotarget. 2017 Mar;:
Adequately defining tumor cell proportion in tissue samples for molecular testing improves interobserver reproducibility of its assessment.
Lhermitte B, Egele C, Weingertner N, Ambrosetti D, Dadone B, Kubiniek V, Burel-Vandenbos F, Coyne J, Michiels JF, Chenard MP, Rouleau E, Sabourin JC, Bellocq JP
Virchows Arch.. 2017 Jan;470(1):21-27
Differentiation of vestibular schwannomas from meningiomas of the internal auditory canal using perilymphatic signal evaluation on T2-weighted gradient-echo fast imaging employing steady state acquisition at 3T.
Venkatasamy A, Le Foll D, Karol A, Lhermitte B, Charpiot A, Debry C, Proust F, Meyer N, Veillon F
Eur Radiol Exp. 2017 ;1(1):8
An unusual pituitary stalk lesion: What is the place of surgery?
Todeschi J, Chibbaro S, Clavier JB, Lhermitte B, Goichot B, Proust F
Neurochirurgie. 2016 Dec;62(6):339-343
Phase II Study of Radiotherapy and Temsirolimus versus Radiochemotherapy with Temozolomide in Patients with Newly Diagnosed Glioblastoma without MGMT Promoter Hypermethylation (EORTC 26082).
Wick W, Gorlia T, Bady P, Platten M, van den Bent MJ, Taphoorn MJ, Steuve J, Brandes AA, Hamou MF, Wick A, Kosch M, Weller M, Stupp R, Roth P, Golfinopoulos V, Frenel JS, Campone M, Ricard D, Marosi C, Villa S, Weyerbrock A, Hopkins K, Homicsko K, Lhermitte B, Pesce G, Hegi ME
Clin. Cancer Res.. 2016 Oct 1;22(19):4797-4806
Clear cell papillary renal cell carcinoma and renal angiomyoadenomatous tumor: two variants of a morphologic, immunohistochemical, and genetic distinct entity of renal cell carcinoma.
Deml KF, Schildhaus HU, Compérat E, von Teichman A, Storz M, Schraml P, Bonventre JV, Fend F, Fleige B, Nerlich A, Gabbert HE, GaBler N, Grobholz R, Hailemariam S, Hinze R, Knüchel R, Lhermitte B, Nesi G, Rüdiger T, Sauter G, Moch H
Am. J. Surg. Pathol.. 2015 Jul;39(7):889-901
Two cilengitide regimens in combination with standard treatment for patients with newly diagnosed glioblastoma and unmethylated MGMT gene promoter: results of the open-label, controlled, randomized phase II CORE study.
Nabors LB, Fink KL, Mikkelsen T, Grujicic D, Tarnawski R, Nam DH, Mazurkiewicz M, Salacz M, Ashby L, Zagonel V, Depenni R, Perry JR, Hicking C, Picard M, Hegi ME, Lhermitte B, Reardon DA
Neuro-oncology. 2015 May;17(5):708-17