Fiche personne
Territoire
Franche-Comté
Statut
Hospitalo-Universitaire
Équipes/plateformes
Equipe Inserm CIC-BT 1431 (Centre d'Investigation Clinique - BioThérapie)
Publications
IL-17 inhibitors in axial spondyloarthritis. An overview.
Toussirot E, Felten R
Expert Opin Biol Ther. 2024 08 17;:
Concordance and agreement between different activity scores in polymyalgia rheumatica.
D'Agostino J, Souki A, Lohse A, Carvajal Alegria G, Dernis E, Richez C, Truchetet ME, Wendling D, Toussirot E, Perdriger A, Gottenberg JE, Felten R, Fautrel B, Chiche L, Hilliquin P, Le Henaff C, Dervieux B, Direz G, Chary-Valckenaere I, Cornec D, Guellec D, Marhadour T, Nowak E, Saraux A, Devauchelle-Pensec V
RMD Open. 2024 03 15;10(1):
Areal bone mineral density, trabecular bone score and 3D-DXA analysis of proximal femur in psoriatic disease.
Toussirot E, Winzenrieth R, Aubin F, Wendling D, Vauchy C, Desmarets M
Front Med (Lausanne). 2024 01 30;11:1341077
Current Pharmacological Therapies for the Management of Spondyloarthritis: Special Considerations in Older Patients.
Felten R, Toussirot E
Drugs Aging. 2023 10 30;:
Editorial: Impact and consequences of COVID-19 on the musculoskeletal system.
Toussirot E, Maglio M, Fini M, Salamanna F
Front Med (Lausanne). 2023 09 22;10:1288778
Evolution of monoclonal gammopathy of undetermined significance in patients treated with JAK inhibitors for rheumatic diseases: data from the MAJIK-SFR registry.
Faganello D, Bertrand A, Meunier P, Avouac J, Toussirot E, Coury F, Seror R, Le Mélédo G, Germain V, Dellal A, Shima D, Hulin C, Prati C, Schaeverbeke T, Richez C, Truchetet ME, Kostine M
Rheumatology (Oxford). 2023 08 4;:
ATHLETIQUE: interest of an adapted physical activity program in patients with juvenile idiopathic arthritis: a feasibility and preliminary effectiveness study.
Py S, Maylié F, Parmentier AL, Vidal C, Cuinet B, Mauny F, Lohse A, Toussirot E, Yoshimasa S, Tordi N, Binda D, Ballot-Schmit C
Front Immunol. 2023 06 27;14:1213799
Advances in pharmacotherapies for axial spondyloarthritis.
Toussirot E
Expert Opin Pharmacother. 2023 06 15;:
Early, very high-titre convalescent plasma therapy in clinically vulnerable individuals with mild COVID-19 (COVIC-19): protocol for a randomised, open-label trial.
Desmarets M, Hoffmann S, Vauchy C, Rijnders BJA, Toussirot E, Durrbach A, Körper S, Schrezenmeier E, van der Schoot CE, Harvala H, Brunotte G, Appl T, Seifried E, Tiberghien P, Bradshaw D, Roberts DJ, Estcourt LJ, Schrezenmeier H
BMJ Open. 2023 04 27;13(4):e071277
The Influence of Adipokines on Radiographic Damage in Inflammatory Rheumatic Diseases.
Toussirot E
Biomedicines. 2023 02 13;11(2):
Fractures reduction with osteoporotic treatments in patients over 75-year-old: A systematic review and meta-analysis.
Guillaumin M, Poirson B, Gerazime A, Puyraveau M, Tannou T, Mauny F, Toussirot É
Front Aging. 2022 11 2;3:845886
Effect of Tocilizumab on Disease Activity in Patients With Active Polymyalgia Rheumatica Receiving Glucocorticoid Therapy: A Randomized Clinical Trial.
Devauchelle-Pensec V, Carvajal-Alegria G, Dernis E, Richez C, Truchetet ME, Wendling D, Toussirot E, Perdriger A, Gottenberg JE, Felten R, Fautrel BJ, Chiche L, Hilliquin P, Le Henaff C, Dervieux B, Direz G, Chary-Valckenaere I, Cornec D, Guellec D, Marhadour T, Nowak E, Saraux A
JAMA. 2022 09 20;328(11):1053-1062
The cardiometabolic conditions of psoriatic disease.
Toussirot E, Gallais-Sérézal I, Aubin F
Front Immunol. 2022 09 8;13:970371
Lack of association between the TNFAIP3 rs2230926 variant and rheumatoid arthritis-associated lymphoma.
Kedra J, Seror R, Dieudé P, Constantin A, Toussirot E, Kfoury E, Masson C, Cornec D, Dubost JJ, Marguerie L, Ottaviani S, Grados F, Belkhir R, Fain O, Fautrel B, Philippe P, Piperno M, Combe B, Lambotte O, Richez C, Sellam J, Sené T, Denis G, Lequerre T, Lazure T, Mariette X, Nocturne G
Joint Bone Spine. 2022 Apr 28;:105390
The Use of Janus Kinase Inhibitors in Axial Spondyloarthritis: Current Insights.
Toussirot E
Pharmaceuticals (Basel). 2022 Feb 22;15(3):
Abatacept as Adjunctive Therapy in Refractory Polymyalgia Rheumatica.
Toussirot E, Michaud M, Wendling D, Devauchelle V
J Rheumatol. 2021 Sep 15;:
Lymphoma complicating rheumatoid arthritis: results from a French case-control study.
Kedra J, Seror R, Dieudé P, Constantin A, Toussirot E, Kfoury E, Masson C, Cornec D, Dubost JJ, Marguerie L, Ottaviani S, Grados F, Belkhir R, Fain O, Goupille P, Sordet C, Fautrel B, Philippe P, Piperno M, Combe B, Lambotte O, Richez C, Sellam J, Sené T, Denis G, Lequerre T, Lazure T, Mariette X, Nocturne G
RMD Open. 2021 09;7(3):
Convalescent plasma to treat COVID-19: Following the Argentinian lead.
Tiberghien P, Toussirot E, Richard P, Morel P, Garraud O
Transfus Apher Sci. 2021 06;60(3):103161
Editorial: Recent Advances in Potential Biomarkers for Rheumatic Diseases and in Cell-Based Therapies in the Management of Inflammatory Rheumatic Diseases.
Saas P, Toussirot E, Bogunia-Kubik K
Front Immunol. 2021 ;12:836119
Mini-Review: The Administration of Apoptotic Cells for Treating Rheumatoid Arthritis: Current Knowledge and Clinical Perspectives.
Toussirot E, Bonnefoy F, Vauchy C, Perruche S, Saas P
Front Immunol. 2021 ;12:630170
The Risk of Cardiovascular Diseases in Axial Spondyloarthritis. Current Insights.
Toussirot E
Front Med (Lausanne). 2021 ;8:782150
Visceral adiposity in patients with psoriatic arthritis and psoriasis alone and its relationship with metabolic and cardiovascular risk.
Toussirot E, Aubin F, Desmarets M, Wendling D, Augé B, Gillard J, Messica O, Guillot X, Laheurte C, Monnet E, Dumoulin G
Rheumatology (Oxford). 2020 Nov 24;:
Sustained remission of ankylosing spondylitis following intravesical Bacillus Calmette et Guérin immunotherapy for bladder cancer.
Toussirot E, Guichard G, Saas P
Clin Exp Rheumatol. 2020 Nov 22;:
Rituximab for rheumatoid arthritis-associated large granular lymphocytic leukemia, a retrospective case series.
Lobbes H, Dervout C, Toussirot E, Felten R, Sibilia J, Wendling D, Gombert B, Ruivard M, Grobost V, Saraux A, Cornec D, Verhoeven F, Soubrier M
Semin Arthritis Rheum. 2020 10;50(5):1109-1113
Increased high molecular weight adiponectin and lean mass during tocilizumab treatment in patients with rheumatoid arthritis: a 12-month multicentre study.
Toussirot E, Marotte H, Mulleman D, Cormier G, Coury F, Gaudin P, Dernis E, Bonnet C, Damade R, Grauer JL, Abdesselam TA, Guillibert-Karras C, Lioté F, Hilliquin P, Sacchi A, Wendling D, Le Goff B, Puyraveau M, Dumoulin G
Arthritis Res Ther. 2020 09 29;22(1):224
Tocilizumab failure in malignancy-related polymyalgia rheumatica.
Toussirot E, Govindaraju S, Mekinian A
Joint Bone Spine. 2020 07;87(4):366-368
L5 Radiculopathy with Neurological Deficit Due To Sacral Insufficiency Fracture.
Toussirot E, Bereau M, Aubry S
J Rheumatol. 2020 06 1;47(6):939-940
Spondyloarthritis-Associated IgA Nephropathy.
Champtiaux N, Lioté F, El Karoui K, Vigneau C, Miceli C, Cornec-Le Gall E, Rémy P, Choukroun G, Fakhouri F, Garrouste C, Veillon L, Pillebout E, Lobbedez T, Vuiblet V, Wynckel A, Guincestre T, Toussirot E, Thervet E, Rabant M, Karras A
Kidney Int Rep. 2020 Jun;5(6):813-820
An unusual association of CANOMAD and rheumatoid arthritis with a long-term follow-up.
Toussirot E, Bereau M, Sevrin P, Tatu L
Joint Bone Spine. 2020 05;87(3):263-264
The Interrelations between Biological and Targeted Synthetic Agents Used in Inflammatory Joint Diseases, and Obesity or Body Composition.
Toussirot E
Metabolites. 2020 Mar 13;10(3):
Mini-Review: The Contribution of Adipokines to Joint Inflammation in Inflammatory Rheumatic Diseases.
Toussirot E
Front Endocrinol (Lausanne). 2020 ;11:606560
Pharmacological management of axial spondyloarthritis in adults.
Toussirot E
Expert Opin Pharmacother. 2019 Aug;20(12):1483-1491
Anti-neutrophil cytoplasmic antibody-associated chronic inflammatory arthritis without vasculitis. Data from a French nationwide survey.
Carvajal Alegria G, Groh M, Guellec D, Toussirot E, Rigaud J, Soubrier M, Ottaviani S, Direz G, Saraux A, Cornec D,
Autoimmun Rev. 2018 12;17(12):1268-1269
Unilateral Accessory Sacroiliac Joint with Bone Marrow Edema Mimicking Sacroiliitis.
Toussirot E, Aubry S, Runge M
J Rheumatol. 2018 08;45(9):1327-1328
Could Sodium Chloride be an Environmental Trigger for Immune-Mediated Diseases? An Overview of the Experimental and Clinical Evidence.
Toussirot E, Béreau M, Vauchy C, Saas P
Front Physiol. 2018 ;9:440
Increased IL-22- and IL-17A-Producing Mucosal-Associated Invariant T Cells in the Peripheral Blood of Patients With Ankylosing Spondylitis.
Toussirot É, Laheurte C, Gaugler B, Gabriel D, Saas P
Front Immunol. 2018 ;9:1610
Ixekizumab: an anti- IL-17A monoclonal antibody for the treatment of psoriatic arthritis.
Toussirot E
Expert Opin Biol Ther. 2018 01;18(1):101-107
MAIT cells: potent major cellular players in the IL-17 pathway of spondyloarthritis?
Toussirot E, Saas P
RMD Open. 2018 ;4(2):e000821
Biologics in myelodysplastic syndrome-related systemic inflammatory and autoimmune diseases: French multicenter retrospective study of 29 patients.
Mekinian A, Dervin G, Lapidus N, Kahn JE, Terriou L, Liozon E, Grignano E, Piette JC, Rauzy OB, Grobost V, Godmer P, Gillard J, Rossignol J, Launay D, Aouba A, Cardon T, Bouillet L, Broner J, Vinit J, Ades L, Carrat F, Salvado C, Toussirot E, Versini M, Costedoat-Chalumeau N, Fraison JB, Guilpain P, Fenaux P, Fain O,
Autoimmun Rev. 2017 Sep;16(9):903-910
Paradoxical elevation of serum TRACP5b levels despite increase in lumbar spine bone mineral density during anti-TNFα therapy in patients with inflammatory rheumatic disease: a 2-year prospective assessment of bone mass, bone metabolism, and the trabecular
Toussirot É, Mourot L, Dehecq B, Michel F, Wendling D, Grandclément É, Dumoulin G
Eur J Rheumatol. 2017 Sep;4(3):189-193
Serum adipokines, adipose tissue measurements and metabolic parameters in patients with advanced radiographic knee osteoarthritis.
Toussirot E, Michel F, Béreau M, Dehecq B, Gaugler B, Wendling D, Grandclément E, Saas P, Dumoulin G
Clin. Rheumatol.. 2017 Aug;:
New treatment options and emerging drugs for axial spondyloarthritis: biological and targeted synthetic agents.
Toussirot E
Expert Opin Pharmacother. 2017 Feb;18(3):275-282
Harnessing Apoptotic Cell Clearance to Treat Autoimmune Arthritis.
Saas P, Bonnefoy F, Toussirot E, Perruche S
Front Immunol. 2017 ;8:1191
New-onset vitiligo and progression of pre-existing vitiligo during treatment with biological agents in chronic inflammatory diseases.
Méry-Bossard L, Bagny K, Chaby G, Khemis A, Maccari F, Marotte H, Perrot JL, Reguiai Z, Sigal ML, Avenel-Audran M, Boyé T, Grasland A, Gillard J, Jullien D, Toussirot E
J Eur Acad Dermatol Venereol. 2017 Jan;31(1):181-186
Switching from originator biological agents to biosimilars: what is the evidence and what are the issues?
Toussirot E, Marotte H
RMD Open. 2017 ;3(2):e000492
Apoptotic cell infusion treats ongoing collagen-induced arthritis, even in the presence of methotrexate, and is synergic with anti-TNF therapy.
Bonnefoy F, Daoui A, Valmary-Degano S, Toussirot E, Saas P, Perruche S
Arthritis Res. Ther.. 2016 Aug;18(1):184
Multiple paradoxical adverse events in a patient with ankylosing spondylitis treated with adalimumab.
Toussirot É, Charollais R, Aubin F
Eur J Dermatol. 2016 Aug;26(4):406-8
Tocilizumab in Giant Cell Arteritis: A Multicenter Retrospective Study of 34 Patients.
Régent A, Redeker S, Deroux A, Kieffer P, Ly KH, Dougados M, Liozon E, Larroche C, Guillevin L, Bouillet L, Espitia O, Costedoat-Chalumeau N, Soubrier M, Brihaye B, Lifermann F, Lefevre G, Puéchal X, Mouthon L, Toussirot E,
J Rheumatol. 2016 08;43(8):1547-52
Hidradenitis suppurativa (HS): An unrecognized paradoxical effect of biologic agents (BA) used in chronic inflammatory diseases.
Faivre C, Villani AP, Aubin F, Lipsker D, Bottaro M, Cohen JD, Durupt F, Jeudy G, Sbidian E, Toussirot E, Badot V, Barbarot S, Debarbieux S, Delaporte E, Goegebeur G, Morel J, Nassif A, Duru G, Jullien D,
J. Am. Acad. Dermatol.. 2016 Jun;74(6):1153-9
Systemic inflammatory and autoimmune manifestations associated with myelodysplastic syndromes and chronic myelomonocytic leukaemia: a French multicentre retrospective study.
Mekinian A, Grignano E, Braun T, Decaux O, Liozon E, Costedoat-Chalumeau N, Kahn JE, Hamidou M, Park S, Puéchal X, Toussirot E, Falgarone G, Launay D, Morel N, Trouiller S, Mathian A, Gombert B, Schoindre Y, Lioger B, De Wazieres B, Amoura Z, Buchdaul AL, Georgin-Lavialle S, Dion J, Madaule S, Raffray L, Cathebras P, Piette JC, Rose C, Ziza JM, Lortholary O, Montestruc F, Omouri M, Denis G, Rossignol J, Nimubona S, Adès L, Gardin C, Fenaux P, Fain O
Rheumatology (Oxford). 2016 Feb;55(2):291-300
Golimumab in radiographic and nonradiographic axial spondyloarthritis: a review of clinical trials.
Toussirot E, Vauchy C, Binda D, Michel F
Drug Des Devel Ther. 2016 ;10:2087-94
Interleukin-6: a promising target for the treatment of polymyalgia rheumatica or giant cell arteritis?
Toussirot É, Régent A, Devauchelle-Pensec V, Saraux A, Puéchal X
RMD Open. 2016 ;2(2):e000305
Paradoxical reactions under TNF-α blocking agents and other biological agents given for chronic immune-mediated diseases: an analytical and comprehensive overview.
Toussirot É, Aubin F
RMD Open. 2016 ;2(2):e000239
Rapid and Sustained Response to Tocilizumab in Patients with Polymyalgia Rheumatica Resistant or Intolerant to Glucocorticoids: A Multicenter Open-label Study.
Toussirot É, Martin A, Soubrier M, Redeker S, Régent A
J Rheumatol. 2016 Jan;43(1):249-50
Dysphagia Related to Esophagus Compression by Anterior Cervical Ossification in a Patient with Ankylosing Spondylitis.
Toussirot É, Mauvais O, Aubry S
J Rheumatol. 2015 Oct;42(10):1922-3
The alternative CD20 transcript variant is not a surrogate marker for resistance to rituximab in patients with rheumatoid arthritis.
Gamonet C, Deschamps M, Marion S, Herbein G, Chiocchia G, Auger I, Saas P, Ferrand C, Toussirot E
Rheumatology (Oxford). 2015 Sep;54(9):1744-5
Diagnosis and Management of Late-Onset Spondyloarthritis: Implications of Treat-to-Target Recommendations.
Toussirot É
Drugs Aging. 2015 Jul;32(7):515-24
Sirt-1 activity in PBMC from patients with spondyloarthritis.
Wendling D, Delattre E, Abbas W, Guillot X, Toussirot E, Herbein G
Joint Bone Spine. 2015 May;82(3):210-1
The role of leptin in the pathophysiology of rheumatoid arthritis.
Toussirot E, Michel F, Binda D, Dumoulin G
Life Sci. 2015 May 26. pii: S0024-3205(15)00257-X
Effects of TNFα inhibitors on adiposity and other cardiovascular risk factors: implications for the cardiovascular prognosis in patients with rheumatoid arthritis.
Toussirot É
Expert Opin Drug Saf. 2015 Apr;14(4):525-32
Biologics in spondyloarthritis: TNFα inhibitors and other agents.
Toussirot É
Immunotherapy. 2015 ;7(6):669-81
Dysregulated serum IL-23 and SIRT1 activity in peripheral blood mononuclear cells of patients with rheumatoid arthritis.
Wendling D, Abbas W, Godfrin-Valnet M, Kumar A, Guillot X, Khan KA, Vidon C, Coquard L, Toussirot E, Prati C, Herbein G
PLoS ONE. 2015 ;10(3):e0119981
New CD20 alternative splice variants: molecular identification and differential expression within hematological B cell malignancies.
Gamonet C, Bole-Richard E, Delherme A, Aubin F, Toussirot E, Garnache-Ottou F, Godet Y, Ysebaert L, Tournilhac O, Caroline D, Larosa F, Deconinck E, Saas P, Borg C, Deschamps M, Ferrand C
Exp Hematol Oncol. 2015 ;5:7
Rhabdomyolysis Occurring under Statins after Intense Physical Activity in a Marathon Runner.
Toussirot É, Michel F, Meneveau N
Case Rep Rheumatol. 2015 ;2015:721078
Vaccination and Induction of Autoimmune Diseases.
Toussirot É, Bereau M
Inflamm Allergy Drug Targets. 2015 ;14(2):94-8
Association of mastocytosis with inflammatory joint diseases: a series of 31 patients.
Bader-Meunier B, Bulai Livideanu C, Larroche C, Durieu I, Artru L, Beucher A, Cormier G, Cornec D, Delarco M, Dubost JJ, Fontaine C, Gourin MP, Javier RM, de Jauréguiberry JP, Maisonneuve H, Toussirot E, Ugo V, Echaubard S, Mahlaoui N, Aouba A, Bodemer C, Briot K, Frenzel L, Lortholary O, Chandesris MO, Hermine O,
Semin Arthritis Rheum. 2014 Dec;44(3):362-5
Biological treatments given in patients with rheumatoid arthritis or ankylosing spondylitis modify HAT/HDAC (histone acetyltransferase/histone deacetylase) balance.
Toussirot E, Wendling D, Herbein G,
Joint Bone Spine. 2014 Dec;81(6):544-5
Relationships between Adipose Tissue and Psoriasis, with or without Arthritis.
Toussirot E, Aubin F, Dumoulin G
Front Immunol. 2014 Aug 12;5:368
[Occurrence of vitiligo in a patient with ankylosing spondylitis receiving adalimumab].
Toussirot E, Salard D, Algros MP, Aubin F
Ann Dermatol Venereol. 2013 Dec;140(12):801-2
Ustekinumab in chronic immune-mediated diseases: a review of long term safety and patient improvement.
Toussirot E, Michel F, Bereau M, Binda D
Patient Prefer Adherence. 2013 Apr 26;7:369-77
Adiponectin in autoimmune diseases.
Toussirot E, Binda D, Gueugnon C, Dumoulin G
Curr Med Chem. 2012;19(32):5474-80.
Elevated adiponectin serum levels in women with systemic autoimmune diseases.
Toussirot E, Gaugler B, Bouhaddi M, Nguyen NU, Saas P, Dumoulin G
Mediators Inflamm. 2010;2010:938408
Spondyloarthropathy and chronic B hepatitis. Effect of anti-TNF therapy.
Wendling D, Di Martino V, Prati C, Toussirot E, Herbein G
Joint Bone Spine. 2009 May;76(3):308-11
Increased production of soluble CTLA-4 in patients with spondylarthropathies correlates with disease activity.
Toussirot E, Saas P, Deschamps M, Pouthier F, Perrot L, Perruche S, Chabod J, Tiberghien P, Wendling D
Arthritis Res Ther. 2009;11(4):R101
Increased tartrate-resistant acid phosphatase serum levels in ankylosing spondylitis and relationship with the inflammatory process.
Toussirot E, Dumoulin G, Saas P, Nguyen NU, Le Huede G, Wendling D
Ann Rheum Dis. 2008 Mar;67(3):430-1.
Pedicle stress fracture: an unusual complication of pycnodysostosis.
Ornetti P, Prati C, Fery-Blanco C, Streit G, Toussirot E, Wendling D
Clin Rheumatol. 2008 Mar;27(3):385-7
Adipose tissue, serum adipokines, and ghrelin in patients with ankylosing spondylitis.
Toussirot E, Streit G, Nguyen NU, Dumoulin G, Le Huede G, Saas P, Wendling D
Metabolism. 2007 Oct;56(10):1383-9.
[Hypercalcemia of double origin: association of multiple myeloma and ectopic parathyroidal adenoma].
Fery-Blanco C, Prati C, Ornetti P, Bevalot J, Streit G, Toussirot E, Wendling D
Rev Med Interne. 2007 Jul;28(7):504-6
[Anti TNF-alpha treatment of a refractory polymyositis].
Wendling D, Prati C, Ornetti P, Toussirot E, Streit G
Rev Med Interne. 2007 Mar;28(3):194-5
Bacterial extract (OM-89) specific and non specific immunomodulation in rheumatoid arthritis patients.
Toussirot E, Robinet E, Saas P, Chabod J, Auge B, Cozma G, Tiberghien P, Roudier J, Wendling D
Autoimmunity. 2006 Jun;39(4):299-306.
Decreased levels of serum soluble HLA class I antigens in HLA-B27 positive spondyloarthropathies.
Toussirot E, Saas P, Pariset J, Chabod J, Tiberghien P, Wendling D
Ann Rheum Dis. 2006 Feb;65(2):279-80.
FDG-PET/CT scan of inflammatory spondylodiscitis lesions in ankylosing spondylitis, and short term evolution during anti-tumour necrosis factor treatment.
Wendling D, Blagosklonov O, Streit G, Lehuede G, Toussirot E, Cardot JC
Ann Rheum Dis. 2005 Nov;64(11):1663-5.
Infliximab continuation rates in patients with rheumatoid arthritis in everyday practice.
Wendling D, Materne GE, Michel F, Lohse A, Lehuede G, Toussirot E, Massol J, Woronoff-Lemsi MC
Joint Bone Spine. 2005 Jul;72(4):309-12
Reactivation of a latent precore mutant hepatitis B virus related chronic hepatitis during infliximab treatment for severe spondyloarthropathy.
Wendling D, Auge B, Bettinger D, Lohse A, Le Huede G, Bresson-Hadni S, Toussirot E, Miguet JP, Herbein G, Di Martino V
Ann Rheum Dis. 2005 May;64(5):788-9.