Magnetic resonance evaluation of cardiac thrombi and masses by T1 and T2 mapping: an observational study.
Fiche publication
Date publication
avril 2017
Journal
The international journal of cardiovascular imaging
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GANGI Afshin, Pr ROY Catherine, Pr DE MATHELIN Michel, Pr OHANA Mickaël
Tous les auteurs :
Caspar T, El Ghannudi S, Ohana M, Labani A, Lawson A, Ohlmann P, Morel O, De Mathelin M, Roy C, Gangi A, Germain P
Lien Pubmed
Résumé
The purpose of this work was to evaluate CMR T1 and T2 mapping sequences in patients with intracardiac thrombi and masses in order to assess T1 and T2 relaxometry usefulness and to allow better etiological diagnosis. This observational study of patients scheduled for routine CMR was performed from September 2014 to August 2015. All patients referred to our department for a 1.5 T CMR were screened to participate. T1 mapping were acquired before and after Gadolinium injection; T2 mapping images were obtained before injection. 41 patients were included. 22 presented with cardiac thrombi and 19 with cardiac masses. The native T1 of thrombi was 1037 ± 152 ms (vs 1032 ± 39 ms for myocardium, p = 0.88; vs 1565 ± 88 ms for blood pool, p < 0.0001). T2 were 74 ± 13 ms (vs 51 ± 3 ms for myocardium, p < 0.0001; vs 170 ± 32 ms for blood pool, p < 0.0001). Recent thrombi had a native T1 shorter than old thrombi (911 ± 177 vs 1169 ± 107 ms, p = 0.01). The masses having a shorter T1 than the myocardium were lipomas (278 ± 29 ms), calcifications (621 ± 218 ms), and melanoma (736 ms). All other masses showed T1 values higher than myocardial T1, with T2 consistently >70 ms. T1 and T2 mapping CMR sequences can be useful and represent a new approach for the evaluation of cardiac thrombi and masses.
Mots clés
Cardiac imaging techniques, Cardiac tumors, Heart neoplasms, Magnetic resonance imaging, Thrombus
Référence
Int J Cardiovasc Imaging. 2017 Apr;33(4):551-559