A benchmark study of ab initio gene prediction methods in diverse eukaryotic organisms.
Fiche publication
Date publication
avril 2020
Journal
BMC genomics
Auteurs
Membres identifiés du Cancéropôle Est :
Dr POCH Olivier, Dr THOMPSON Julie, Pr COLLET Pierre
Tous les auteurs :
Scalzitti N, Jeannin-Girardon A, Collet P, Poch O, Thompson JD
Lien Pubmed
Résumé
The draft genome assemblies produced by new sequencing technologies present important challenges for automatic gene prediction pipelines, leading to less accurate gene models. New benchmark methods are needed to evaluate the accuracy of gene prediction methods in the face of incomplete genome assemblies, low genome coverage and quality, complex gene structures, or a lack of suitable sequences for evidence-based annotations.
Mots clés
Benchmark study, Gene prediction, Genome annotation, Protein prediction
Référence
BMC Genomics. 2020 Apr 9;21(1):293