Highly robust hydrogels via a fast, simple and cytocompatible dual crosslinking-based process.
Fiche publication
Date publication
novembre 2015
Journal
Chemical communications (Cambridge, England)
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MANO João F.
Tous les auteurs :
Costa AM, Mano JF
Lien Pubmed
Résumé
A highly robust hydrogel device made from a single biopolymer formulation is reported. Owing to the presence of covalent and non-covalent crosslinks, these engineered systems were able to (i) sustain a compressive strength of ca. 20 MPa, (ii) quickly recover upon unloading, and (iii) encapsulate cells with high viability rates.
Mots clés
Acrylamides, chemistry, Animals, Cell Line, Cell Survival, Chitosan, chemistry, Compressive Strength, Glycerophosphates, chemistry, Hydrogels, chemistry, Materials Testing, Mice, Photosensitizing Agents, chemistry, Ultraviolet Rays
Référence
Chem. Commun. (Camb.). 2015 Nov 7;51(86):15673-6