Effect of Tc elution in vivo from red cells on red cell volumes measured using autologous Tc-labeled red cells: comparison with Cr method.
Fiche publication
Date publication
juin 2020
Journal
Annales de biologie clinique
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GIRODON François
Tous les auteurs :
Gallet M, Drouet C, Girodon F, Nicolas A, Riedinger JM
Lien Pubmed
Résumé
The purpose of this work was to compare the measured red-cell volume (RCV) using sodium pertechnétate [RCV-Tc] compared to the reference technique using sodium radiochromate [RCV-Cr] and to assess the influence of technetium-99 elution on the RCV-Tc value. Ten patients had simultaneous measurements of RCV-Tc and RCV-Cr. Elution of Tc-99m from red blood cells was 2.9% and led to an average overestimation of RCV-Tc of 3.7%. The introduction of individual tracer elution rates in the RCV-Tc calculation corrects this overestimation.
Mots clés
erythrosis, polycythemia vera, red cell volume
Référence
Ann. Biol. Clin. (Paris). 2020 Jun 1;78(3):319-322