Design and evaluation of an abbreviated pixelwise dynamic contrast enhancement analysis protocol for early extracellular volume fraction estimation.

Fiche publication


Date publication

novembre 2020

Journal

Magnetic resonance imaging

Auteurs

Membres identifiés du Cancéropôle Est :
Pr FELBLINGER Jacques, Dr BEAUMONT Marine


Tous les auteurs :
Louis JS, Odille F, Mandry D, De Chillou C, Huttin O, Felblinger J, Venner C, Beaumont M

Résumé

T1-based method is considered as the gold standard for extracellular volume fraction (ECV) mapping. This technique requires at least a 10 min delay after injection to acquire the post injection T1 map. Quantitative analysis of Dynamic Contrast Enhancement (DCE) images could lead to an earlier estimation of an ECV like parameter (2 min). The purpose of this study was to design a quantitative pixel-wise DCE analysis workflow to assess the feasibility of an early estimation of ECV.

Mots clés

Cardiac MR, DCE-MRI, ECV, PERMEABILITY, REGISTRATION

Référence

Magn Reson Imaging. 2020 Nov 20;76:61-68