Extracranial rhabdoid tumours: Results of a SFCE series of patients treated with a dose compression strategy according to European Paediatric Soft tisue sarcoma Study Group recommendations.

Fiche publication


Date publication

décembre 2021

Journal

European journal of cancer (Oxford, England : 1990)

Auteurs

Membres identifiés du Cancéropôle Est :
Dr LACOUR Brigitte


Tous les auteurs :
Enault M, Minard-Colin V, Corradini N, Leverger G, Thebaud E, Rome A, Proust S, Marie-Cardine A, Defachelles AS, Sarnacki S, Philippe-Chomette P, Delattre O, Masliah-Planchon J, Lacour B, Ferrari A, Brennan B, Orbach D, Bourdeaut F

Résumé

Extracranial malignant rhabdoid tumours are tumours that mainly affect young children and have a poor prognosis. In 2014, the European Paediatric Soft-tissue sarcoma Study Group developed treatment recommendations consisting in intensive dose chemotherapy every 2 weeks using vincristine-doxorubicin-cyclophosphamide (VDCy) and ifosfamide-etoposide (IE) associated with early surgery and irradiation of tumour sites.

Mots clés

Children, Dose-intensity, EpSSG, Malignant rhabdoid tumour, SMARCB1

Référence

Eur J Cancer. 2021 Dec 17;161:64-78