Association of cerebral microbleeds with cerebrospinal fluid Alzheimer-biomarkers and clinical symptoms in early dementia with Lewy bodies.
Fiche publication
Date publication
juin 2021
Journal
International journal of geriatric psychiatry
Auteurs
Membres identifiés du Cancéropôle Est :
Dr NOBLET Vincent
Tous les auteurs :
Mendes A, Noblet V, Mondino M, Loureiro de Sousa P, Manji S, Archenault A, Casanovas M, Bousiges O, Philippi N, Baloglu S, Rauch L, Cretin B, Demuynck C, Martin-Hunyadi C, Blanc F
Lien Pubmed
Résumé
To determine the prevalence, localization and associations of cerebral microbleeds (CMB) in dementia with Lewy bodies (DLB) with its core clinical symptoms and cerebrospinal fluid (CSF) biomarkers of Alzheimer's disease (AD). We hypothesize DLB patients with CMB have increased amyloid burden compared to those without CMB, which could also translate into clinical differences.
Mots clés
Alzheimer's disease, CSF biomarkers, Lewy-bodies dementia, cerebral amyloid angiopathy, cerebral microbleeds
Référence
Int J Geriatr Psychiatry. 2021 06;36(6):851-857