Retrospective and integrative analyses of molecular characteristics and their specific imaging parameters in pediatric grade 1 gliomas.
Fiche publication
Date publication
avril 2022
Journal
Pediatric blood & cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CHENARD Marie-Pierre, Pr ENTZ-WERLE Natacha, Dr GUERIN Eric, Dr LHERMITTE Benoît, Dr REITA Damien
Tous les auteurs :
Coutant M, Lhermitte B, Guérin E, Chammas A, Reita D, Sebastia C, Douzal V, Gabor F, Salmon A, Chenard MP, Todeschi J, Coca A, Heng MA, Vincent F, Entz-Werlé N
Lien Pubmed
Résumé
Pediatric low-grade gliomas (PLGG) are the most common brain tumors diagnosed during childhood and represent a heterogeneous group associating variable molecular abnormalities. To go further and develop specific statistical patterns between tumor molecular background, imaging features, and patient outcome, a retrospective study was performed in a group of non-neurofibromatosis type 1 (non-NF1) grade 1 PLGGs.
Mots clés
BRAF, MRI, cyst, grade I gliomas, pediatric
Référence
Pediatr Blood Cancer. 2022 Apr 4;:e29575