3D differential interference contrast microscopy using polarisation sensitive tomographic diffraction microscopy.

Fiche publication


Date publication

novembre 2022

Journal

Journal of microscopy

Auteurs

Membres identifiés du Cancéropôle Est :
Pr HAEBERLE Olivier


Tous les auteurs :
Verrier N, Taddese AM, Abbessi R, Debailleul M, Haeberlé O

Résumé

Tomographic Diffraction Microscopy (TDM) is a generalisation of Digital Holographic Microscopy (DHM), for which the illumination angle onto the sample is fully controlled, which has become a tool of choice for 3-D, high-resolution imaging of unlabelled samples. TDM makes it possible to obtain the optical field in both amplitude and phase for each illumination angle. Proper information reallocation eventually allows for 3D reconstruction of the complex refractive index map. On the other hand, Polarisation Array Sensors (PAS) paves new way for TDM, as vectorial information assessment about the investigated sample. In this contribution, we show an alternative use of this polarisation information based on the phase sensitive nature of TDM. Here, we demonstrated that TDM coupled with PAS can lead to a 3D Differential Interference Contrast (DIC) microscope with almost no experimental configuration modification. This article is protected by copyright. All rights reserved.

Mots clés

holography, microscopy, tomography

Référence

J Microsc. 2022 11 21;: