PAX-FOXO1 fusion status in children and adolescents with alveolar rhabdomyosarcoma: Impact on clinical, pathological, and survival features.
Fiche publication
Date publication
janvier 2023
Journal
Pediatric blood & cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DESANDES Emmanuel, Dr LACOUR Brigitte
Tous les auteurs :
Raze T, Lapouble E, Lacour B, Guissou S, Defachelles AS, Gaspar N, Delattre O, Pierron G, Desandes E
Lien Pubmed
Résumé
Alveolar rhabdomyosarcoma (ARMS) is an aggressive pediatric cancer and cases with fusion PAX3-FOXO1 and PAX7-FOXO1 seem to have a poor prognosis. The aim is to evaluate whether PAX-FOXO1 alterations influence clinical outcome in childhood and adolescence population with ARMS.
Mots clés
PAX-FOXO1, adolescents, alveolar rhabdomyosarcoma, children, prognosis
Référence
Pediatr Blood Cancer. 2023 01 31;:e30228