Novel Natrosol/Pectin-co-poly (acrylate) based pH-responsive polymeric carrier system for controlled delivery of Tapentadol Hydrochloride.
Fiche publication
Date publication
août 2023
Journal
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
Auteurs
Membres identifiés du Cancéropôle Est :
Dr ERNST Barbara
Tous les auteurs :
Zafar N, Mahmood A, Ilyas S, Ijaz H, Muhammad Sarfraz R, Mahdi WA, Salem-Bekhit MM, Ibrahim MA, Benguerba Y, Ernst B
Lien Pubmed
Résumé
This study aimed to create a controlled delivery system for Tapentadol Hydrochloride by developing interpenetrating networks (IPNs) of Natrosol-Pectin copolymerized with Acrylic Acid and Methylene bisacrylamide, and to analyze the effects of various ingredients on the physical and chemical characteristics of the IPNs.
Mots clés
Controlled release, Interpenetrating network, Natrosol, Pectin, Tapentadol Hydrochloride
Référence
Saudi Pharm J. 2023 08;31(8):101671