Interrelationships between the kinetics of VLDL subspecies and HDL catabolism in abdominal obesity: a multicenter tracer kinetic study.
Fiche publication
Date publication
novembre 2014
Journal
The Journal of clinical endocrinology and metabolism
Auteurs
Membres identifiés du Cancéropôle Est :
Pr DUVILLARD Laurence, Pr VERGES Bruno
Tous les auteurs :
Vergès B, Adiels M, Boren J, Barrett PH, Watts GF, Chan D, Duvillard L, Söderlund S, Matikainen N, Kahri J, Robin I, Taskinen MR
Lien Pubmed
Résumé
Low plasma high-density lipoprotein (HDL) cholesterol is a major abnormality in abdominal obesity. This relates due to accelerated HDL catabolism, but the underlying mechanism requires further elucidation. The relationships between HDL catabolism and other variables that may be modified in abdominal obesity, such as very low-density lipoprotein (VLDL) subspecies (VLDL1, VLDL2) kinetics, liver fat, or visceral adiposity, remain to be investigated.
Mots clés
Adipose Tissue, metabolism, Adult, Aged, Apolipoproteins, metabolism, Female, Humans, Lipoproteins, HDL, metabolism, Lipoproteins, VLDL, metabolism, Liver, metabolism, Male, Middle Aged, Obesity, Abdominal, metabolism
Référence
J. Clin. Endocrinol. Metab.. 2014 Nov;99(11):4281-90