Structuring and Molding of Electrospun Nanofibers: Effect of Electrical and Topographical Local Properties of Micro-Patterned Collectors.

Fiche publication


Date publication

octobre 2012

Auteurs

Membres identifiés du Cancéropôle Est :
Dr BENKIRANE-JESSEL Nadia


Tous les auteurs :
Lavielle N, Hebraud A, Mendoza-Palomares C, Ferrand A, Benkirane-Jessel N, Schlatter G

Résumé

The controlled deposition of electrospun nanofibers at the micro-scale is studied. Several collectors with microscopic patterns are prepared using photolithography. Nanofiber deposition is influenced by the geometry, the size, and the distance between micro-patterns. Within certain conditions, membranes with multiple micro spider-webs or perpendicularly interconnected microgrids are obtained. Dielectric micro-holes having a conductive bottom can be filled by the nanofiber. This kind of micro-molding is rationalized using simulations that show the influence of the collector relative permittivity on the electric field at the pattern vicinity. Micro-woven membranes of PCL with good mechanical properties can be produced, allowing their use for biomedical applications in tissue engineering.

Référence

. 2012 Oct;297(10):958-68.