Factors affecting the detectability of myocardial activity on a semiconductors camera.
Fiche publication
Date publication
février 2012
Auteurs
Membres identifiés du Cancéropôle Est :
Pr KARCHER Gilles
Tous les auteurs :
Verger A, Imbert L, Morel O, Poussier S, Djaballah W, Koehl G, Karcher G, Marie PY
Lien Pubmed
Résumé
Body weight was already shown to be a major factor for the delectability of myocardial activity with conventional cameras and thus, for the optimization of injected activities and or recording times. This study was aimed to identify the factors affecting this detectability on a new solid-state camera showing a high sensitivity of detection (D.SPECT camera Cyclopharma (R)). Patients and methods. - The study population involved 101 patients, who underwent myocardial SPECT with Sestamibi on a one-day stress/rest protocol. Each conventional acquisition (DST-XL General Electric Healthcare (R) USA) was immediately followed by a D-SPECT (R) one. Myocardial activity was determined on each acquisition in counts per seconds and expressed in fraction of the injected activity for assessing the detectability of myocardial activity. Results. - Myocardial activity was on average 12 +/- 3 fold higher when recorded with the D-SPECT (R) camera than with the DST-XL (R) one. Body weight and especially body mass index (BMI) were the most significant correlates of the detectability of myocardial activity for both cameras. According to these correlations, an increase in the BMI from 25 to 35 kg/m was associated with a 47% decrease in the detectability of myocardial activity at stress with the DST-XL (R) and of only 30% with the D-SPECT. Conclusion. - The detectability of myocardial activity provided by the D.SPECT camera is dramatically higher than that documented for conventional cameras of the DST-XL type and is affected by the increase in body weight and in body mass index but at a lower rate than for the Anger camera. (C) 2011 Elsevier Masson SAS. All rights reserved.
Référence
. 2012 Feb;36(2):62-8.