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Recherche

Expertises :
- Recherche:Pharmacologie
- Recherche:Biologie Cellulaire
- Recherche:Biologie Moléculaire
- Recherche:Modèle animaux
- Cancer:Cerveau

Projets


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Publications


Quest for a stable Cu-ligand complex with a high catalytic activity to produce ROS.

Bouraguba M, Schmitt AM, Suseela YV, Vileno B, Melin F, Glattard E, Orvain C, Lebrun V, Raibaut L, Ilbert M, Bechinger B, Hellwig P, Gaiddon C, Sour A, Faller P

Metallomics. 2024 04 13;:

The unfolded protein response-glutathione metabolism axis: A novel target of a cycloruthenated complexes bypassing tumor resistance mechanisms.

Riegel G, Orvain C, Recberlik S, Spaety ME, Poschet G, Venkatasamy A, Yamamoto M, Nomura S, Tsukamoto T, Masson M, Gross I, Le Lagadec R, Mellitzer G, Gaiddon C

Cancer Lett. 2024 01 28;:216671

Altering relative metal-binding affinities in multifunctional Metallochaperones for mutant p53 reactivation.

Kwan K, Castro-Sandoval O, Ma B, Martelino D, Saffari A, Liu XL, Orvain C, Mellitzer G, Gaiddon C, Storr T

J Inorg Biochem. 2023 11 22;251:112433

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