Dr LAMOUR Valérie

Fiche personne

Coordonnées

IGBMC
1 rue Laurent Fries
BP 10142
67404 ILLKIRCH
FRANCE

+33 3 69 48 52 81

Territoire

Alsace

Statut

Hospitalo-Universitaire

Affiliation

IGBMC - Institut de génétique et de biologie moléculaire et cellulaire (IGBMC)

Équipes/plateformes

Equipe Equipe "Biologie structurale intégrative / Stabilité de la chromatine et mobilité de l'ADN"

Recherche

Expertises :
- Recherche:Biologie Structurale

Projets

Identification et étude de l'architecture des complexes associés aux ADN topoisomérases, cibles cellulaires de chimiothérapie des cancers

2012 - Porteur du projet : Dr LAMOUR Valérie

Publications

Structural basis of DNA crossover capture by DNA gyrase.

Vayssières M, Marechal N, Yun L, Lopez Duran B, Murugasamy NK, Fogg JM, Zechiedrich L, Nadal M, Lamour V

Science. 2024 04 12;384(6692):227-232

What's on the Other Side of the Gate: A Structural Perspective on DNA Gate Opening of Type IA and IIA DNA Topoisomerases.

Vidmar V, Vayssières M, Lamour V

Int J Mol Sci. 2023 02 16;24(4):

The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans.

Daiß JL, Pilsl M, Straub K, Bleckmann A, Höcherl M, Heiss FB, Abascal-Palacios G, Ramsay EP, Tlučková K, Mars JC, Fürtges T, Bruckmann A, Rudack T, Bernecky C, Lamour V, Panov K, Vannini A, Moss T, Engel C

Life Sci Alliance. 2022 11;5(11):

Structural basis for allosteric regulation of Human Topoisomerase IIα.

Vanden Broeck A, Lotz C, Drillien R, Haas L, Bedez C, Lamour V

Nat Commun. 2021 05 20;12(1):2962

Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes.

Huang SN, Michaels SA, Mitchell BB, Majdalani N, Vanden Broeck A, Canela A, Tse-Dinh YC, Lamour V, Pommier Y

Sci Adv. 2021 Mar;7(10):

The interplay between DNA topoisomerase 2α post-translational modifications and drug resistance.

Lotz C, Lamour V

Cancer Drug Resist. 2020 02 27;3(2):149-160

Cryo-EM structure of the complete E. coli DNA gyrase nucleoprotein complex.

Vanden Broeck A, Lotz C, Ortiz J, Lamour V

Nat Commun. 2019 Oct 30;10(1):4935

Structural Basis for DNA Gyrase Interaction with Coumermycin A1.

Vanden Broeck AP, McEwen AG, Chebaro Y, Potier N, Lamour V

J. Med. Chem.. 2019 Mar 28;:

Publisher Correction: Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain.

Bedez C, Lotz C, Batisse C, Broeck AV, Stote RH, Howard E, Pradeau-Aubreton K, Ruff M, Lamour V

Sci Rep. 2018 Jul 10;8(1):10673

Post-translational modifications in DNA topoisomerase 2α highlight the role of a eukaryote-specific residue in the ATPase domain.

Bedez C, Lotz C, Batisse C, Broeck AV, Stote RH, Howard E, Pradeau-Aubreton K, Ruff M, Lamour V

Sci Rep. 2018 Jun 18;8(1):9272

A no-stop mutation in MAGEB4 is a possible cause of rare X-linked azoospermia and oligozoospermia in a consanguineous Turkish family.

Okutman O, Muller J, Skory V, Garnier JM, Gaucherot A, Baert Y, Lamour V, Serdarogullari M, Gultomruk M, Röpke A, Kliesch S, Herbepin V, Aknin I, Benkhalifa M, Teletin M, Bakircioglu E, Goossens E, Charlet-Berguerand N, Bahceci M, Tüttelmann F, Viville S

J. Assist. Reprod. Genet.. 2017 Apr;: