Georgievski A, Bellaye PS, Tournier B, Choubley H, Pais de Barros JP, Herbst M, Béduneau A, Callier P, Collin B, Végran F, Ballerini P, Garrido C, Quéré R

Cell Death Dis. 2024 05 11;15(5):328

Bone marrow-derived extracellular vesicles carry the TGF-β signal transducer Smad2 to preserve hematopoietic stem cells in mice.

Gautheron F, Georgievski A, Garrido C, Quéré R

Cell Death Discov. 2023 04 5;9(1):117

Heat-Shock Proteins in Leukemia and Lymphoma: Multitargets for Innovative Therapeutic Approaches.

Cabaud-Gibouin V, Durand M, Quéré R, Girodon F, Garrido C, Jego G

Cancers (Basel). 2023 02 3;15(3):

Acute lymphoblastic leukemia-derived extracellular vesicles affect quiescence of hematopoietic stem and progenitor cells.

Georgievski A, Michel A, Thomas C, Mlamla Z, Pais de Barros JP, Lemaire-Ewing S, Garrido C, Quéré R

Cell Death Dis. 2022 Apr 12;13(4):337

HSP90 inhibitor NVP-BEP800 affects stability of SRC kinases and growth of T-cell and B-cell acute lymphoblastic leukemias.

Mshaik R, Simonet J, Georgievski A, Jamal L, Bechoua S, Ballerini P, Bellaye PS, Mlamla Z, Pais de Barros JP, Geissler A, Francin PJ, Girodon F, Garrido C, Quéré R

Blood Cancer J. 2021 Mar 18;11(3):61

High-fat diet intensifies MLL-AF9-induced acute myeloid leukemia through activation of the FLT3 signaling in mouse primitive hematopoietic cells.

Hermetet F, Mshaik R, Simonet J, Callier P, Delva L, Quéré R

. 2020 Sep 30;10(1):16187

T-cell acute lymphoblastic leukemia displays autocrine production of Interleukin-7.

Buffière A, Uzan B, Aucagne R, Hermetet F, Mas M, Nassurdine S, Aznague A, Carmignac V, Tournier B, Bouchot O, Ballerini P, Barata JT, Bastie JN, Delva L, Pflumio F, Quéré R

Oncogene. 2019 Aug 15;:

Effects of assisted reproductive technologies on transposon regulation in the mouse pre-implanted embryo.

Carmignac V, Barberet J, Iranzo J, Quéré R, Guilleman M, Bourc'his D, Fauque P

Hum. Reprod.. 2019 Mar 13;:

High-fat diet disturbs lipid raft/TGF-β signaling-mediated maintenance of hematopoietic stem cells in mouse bone marrow.

Hermetet F, Buffière A, Aznague A, Pais de Barros JP, Bastie JN, Delva L, Quéré R

Nat Commun. 2019 Jan 31;10(1):523

LPCAT3 deficiency in hematopoietic cells alters cholesterol and phospholipid homeostasis and promotes atherosclerosis.

Thomas C, Jalil A, Magnani C, Ishibashi M, Queré R, Bourgeois T, Bergas V, Ménégaut L, Patoli D, Le Guern N, Labbé J, Gautier T, de Barros JPP, Lagrost L, Masson D

Atherosclerosis. 2018 May 18;:

Saracatinib impairs maintenance of human T-ALL by targeting the LCK tyrosine kinase in cells displaying high level of lipid rafts.

Buffière A, Accogli T, Saint-Paul L, Lucchi G, Uzan B, Ballerini P, Bastie JN, Delva L, Pflumio F, Quéré R

Leukemia. 2018 Feb 28;:

[CD45 phosphatase, a relevant target for the treatment of acute myeloid leukemia].

Saint-Paul L, Nguyen CH, Bastie JN, Delva L, Quéré R

Med Sci (Paris). 2016 Dec;32(12):1051-1053

CD45 phosphatase is crucial for human and murine acute myeloid leukemia maintenance through its localization in lipid rafts.

Saint-Paul L, Nguyen CH, Buffière A, Pais de Barros JP, Hammann A, Landras-Guetta C, Filomenko R, Chrétien ML, Johnson P, Bastie JN, Delva L, Quéré R

Oncotarget. 2016 10;7(40):64785-64797

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Dr QUERE Ronan

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Projets

Identification de biomarqueurs des rechutes thérapeutiques des Leucémies Aiguës Lymphocytaires en isolant les exosomes du plasma

La voie signalétique du CD84 comme nouvelle cible thérapeutique pour le traitement des leucémies aiguës lymphoblastiques pédiatriques

Etude des radeaux lipidiques et de la voie signalétique CLEC2A dans les Leucémies Aiguës Lymphoblastiques (LAL-T) humaines

Identification de nouvelles petites molécules chimiques et voies signalétiques pour le traitement des Leucémies Aiguës Myéloblastiques

Rôle de TIF1gamma dans la leucémie myélomonocytaire chronique

Publications

CD40 agonist on patient-derived xenograft mice for the treatment of B-cell acute lymphoblastic leukemia.

Valrubicin-loaded immunoliposomes for specific vesicle-mediated cell death in the treatment of hematological cancers.