Mokhtari A, Ibrahim EC, Gloaguen A, Barrot CC, Cohen D, Derouin M, Vachon H, Charbonnier G, Loriod B, Decraene C, Yalcin I, Marie-Claire C, Etain B, Belzeaux R, Delahaye-Duriez A, Lutz PE

EBioMedicine. 2025 02 5;113:105569

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment.

Hagihara H, Shoji H, Hattori S, Sala G, Takamiya Y, Tanaka M, Ihara M, Shibutani M, Hatada I, Hori K, Hoshino M, Nakao A, Mori Y, Okabe S, Matsushita M, Urbach A, Katayama Y, Matsumoto A, Nakayama KI, Katori S, Sato T, Iwasato T, Nakamura H, Goshima Y, Raveau M, Tatsukawa T, Yamakawa K, Takahashi N, Kasai H, Inazawa J, Nobuhisa I, Kagawa T, Taga T, Darwish M, Nishizono H, Takao K, Sapkota K, Nakazawa K, Takagi T, Fujisawa H, Sugimura Y, Yamanishi K, Rajagopal L, Hannah ND, Meltzer HY, Yamamoto T, Wakatsuki S, Araki T, Tabuchi K, Numakawa T, Kunugi H, Huang FL, Hayata-Takano A, Hashimoto H, Tamada K, Takumi T, Kasahara T, Kato T, Graef IA, Crabtree GR, Asaoka N, Hatakama H, Kaneko S, Kohno T, Hattori M, Hoshiba Y, Miyake R, Obi-Nagata K, Hayashi-Takagi A, Becker LJ, Yalcin I, Hagino Y, Kotajima-Murakami H, Moriya Y, Ikeda K, Kim H, Kaang BK, Otabi H, Yoshida Y, Toyoda A, Komiyama NH, Grant SGN, Ida-Eto M, Narita M, Matsumoto KI, Okuda-Ashitaka E, Ohmori I, Shimada T, Yamagata K, Ageta H, Tsuchida K, Inokuchi K, Sassa T, Kihara A, Fukasawa M, Usuda N, Katano T, Tanaka T, Yoshihara Y, Igarashi M, Hayashi T, Ishikawa K, Yamamoto S, Nishimura N, Nakada K, Hirotsune S, Egawa K, Higashisaka K, Tsutsumi Y, Nishihara S, Sugo N, Yagi T, Ueno N, Yamamoto T, Kubo Y, Ohashi R, Shiina N, Shimizu K, Higo-Yamamoto S, Oishi K, Mori H, Furuse T, Tamura M, Shirakawa H, Sato DX, Inoue YU, Inoue T, Komine Y, Yamamori T, Sakimura K, Miyakawa T

Elife. 2024 03 26;12:

Dissecting the autism-associated 16p11.2 locus identifies multiple drivers in neuroanatomical phenotypes and unveils a male-specific role for the major vault protein.

Kretz PF, Wagner C, Mikhaleva A, Montillot C, Hugel S, Morella I, Kannan M, Fischer MC, Milhau M, Yalcin I, Brambilla R, Selloum M, Herault Y, Reymond A, Collins SC, Yalcin B

Genome Biol. 2023 11 15;24(1):261

Neuropathic pain: From actual pharmacological treatments to new therapeutic horizons.

Thouaye M, Yalcin I

Pharmacol Ther. 2023 11;251:108546

Janus effect of the anterior cingulate cortex: Pain and emotion.

Journée SH, Mathis VP, Fillinger C, Veinante P, Yalcin I

Neurosci Biobehav Rev. 2023 10;153:105362

The basolateral amygdala-anterior cingulate pathway contributes to depression-like behaviors and comorbidity with chronic pain behaviors in male mice.

Becker LJ, Fillinger C, Waegaert R, Journée SH, Hener P, Ayazgok B, Humo M, Karatas M, Thouaye M, Gaikwad M, Degiorgis L, Santin MDN, Mondino M, Barrot M, Ibrahim EC, Turecki G, Belzeaux R, Veinante P, Harsan LA, Hugel S, Lutz PE, Yalcin I

Nat Commun. 2023 04 17;14(1):2198

Time Course of Homeostatic Structural Plasticity in Response to Optogenetic Stimulation in Mouse Anterior Cingulate Cortex.

Lu H, Gallinaro JV, Normann C, Rotter S, Yalcin I

Cereb Cortex. 2022 04 5;32(8):1574-1592

Platelet-rich plasma and cytokines in neuropathic pain: A narrative review and a clinical perspective.

Bohren Y, Timbolschi DI, Muller A, Barrot M, Yalcin I, Salvat E

Eur J Pain. 2022 01;26(1):43-60

Antiallodynic action of phosphodiesterase inhibitors in a mouse model of peripheral nerve injury.

Megat S, Hugel S, Journée SH, Bohren Y, Lacaud A, Lelièvre V, Doridot S, Villa P, Bourguignon JJ, Salvat E, Schlichter R, Freund-Mercier MJ, Yalcin I, Barrot M

Neuropharmacology. 2021 Dec 4;:108909

Enhanced analgesic cholinergic tone in the spinal cord in a mouse model of neuropathic pain.

Dhanasobhon D, Medrano MC, Becker LJ, Moreno-Lopez Y, Kavraal S, Bichara C, Schlichter R, Inquimbert P, Yalcin I, Cordero-Erausquin M

Neurobiol Dis. 2021 07;155:105363

Mapping the living mouse brain neural architecture: strain-specific patterns of brain structural and functional connectivity.

Karatas M, Noblet V, Nasseef MT, Bienert T, Reisert M, Hennig J, Yalcin I, Kieffer BL, von Elverfeldt D, Harsan LA

Brain Struct Funct. 2021 Apr;226(3):647-669

Action of mefloquine/amitriptyline THN101 combination on neuropathic mechanical hypersensitivity in mice.

Letellier B, Kremer M, Becker LJ, Andry V, Goumon Y, Leboulleux Q, Hener P, Inquimbert P, Couqueberg N, Waltisperger E, Yalcin I, Mouthon F, Droguerre M, Charvériat M, Barrot M

Pain. 2021 Mar 24;:

Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation.

Lutz PE, Chay MA, Pacis A, Chen GG, Aouabed Z, Maffioletti E, Théroux JF, Grenier JC, Yang J, Aguirre M, Ernst C, Redensek A, van Kempen LC, Yalcin I, Kwan T, Mechawar N, Pastinen T, Turecki G

Nat Commun. 2021 02 18;12(1):1132

Depression in focus: Insights from animal and human data, from molecular to behavioural analyses.

Barrot M, Yalcin I

Eur J Neurosci. 2021 01;53(1):5-8

How to study anxiety and depression in rodent models of chronic pain?

Kremer M, Becker LJ, Barrot M, Yalcin I

Eur J Neurosci. 2021 01;53(1):236-270

Long-lasting analgesic and neuroprotective action of the non-benzodiazepine anxiolytic etifoxine in a mouse model of neuropathic pain.

Kamoun N, Gazzo G, Goumon Y, Andry V, Yalcin I, Poisbeau P

Neuropharmacology. 2020 Nov 16;182:108407

Comorbidity of chronic pain and anxiodepressive disorders: Deciphering underlying brain circuits.

Becker LJ, Journée SH, Lutz PE, Yalcin I

Neurosci Biobehav Rev. 2020 08;115:131-133

Ketamine induces rapid and sustained antidepressant-like effects in chronic pain induced depression: Role of MAPK signaling pathway.

Humo M, Ayazgök B, Becker LJ, Waltisperger E, Rantamäki T, Yalcin I

Prog Neuropsychopharmacol Biol Psychiatry. 2020 06 8;100:109898

Peripheral Delta Opioid Receptors Mediate Formoterol Anti-allodynic Effect in a Mouse Model of Neuropathic Pain.

Ceredig RA, Pierre F, Doridot S, Alduntzin U, Hener P, Salvat E, Yalcin I, Gaveriaux-Ruff C, Barrot M, Massotte D

Front Mol Neurosci. 2020 02 14;12:324

Depression and antidepressant action-from molecules to networks.

Rantamäki T, Yalcin I

Cell Tissue Res. 2019 07;377(1):1-4

The molecular neurobiology of chronic pain-induced depression.

Humo M, Lu H, Yalcin I

Cell Tissue Res. 2019 07;377(1):21-43

Cortical Excitability and Activation of TrkB Signaling During Rebound Slow Oscillations Are Critical for Rapid Antidepressant Responses.

Kohtala S, Theilmann W, Rosenholm M, Penna L, Karabulut G, Uusitalo S, Järventausta K, Yli-Hankala A, Yalcin I, Matsui N, Wigren HK, Rantamäki T

Mol Neurobiol. 2019 06;56(6):4163-4174

A Dual Noradrenergic Mechanism for the Relief of Neuropathic Allodynia by the Antidepressant Drugs Duloxetine and Amitriptyline.

Kremer M, Yalcin I, Goumon Y, Wurtz X, Nexon L, Daniel D, Megat S, Ceredig RA, Ernst C, Turecki G, Chavant V, Théroux JF, Lacaud A, Joganah LE, Lelievre V, Massotte D, Lutz PE, Gilsbach R, Salvat E, Barrot M

J. Neurosci.. 2018 Nov 14;38(46):9934-9954

Peripheral delta opioid receptors mediate duloxetine antiallodynic effect in a mouse model of neuropathic pain.

Ceredig RA, Pierre F, Doridot S, Alduntzin U, Salvat E, Yalcin I, Gaveriaux-Ruff C, Barrot M, Massotte D

Eur J Neurosci. 2018 09;48(5):2231-2246

Efferents of anterior cingulate areas 24a and 24b and midcingulate areas 24a' and 24b' in the mouse.

Fillinger C, Yalcin I, Barrot M, Veinante P

Brain Struct Funct. 2018 05;223(4):1747-1778

Hyperactivity of Anterior Cingulate Cortex Areas 24a/24b Drives Chronic Pain-Induced Anxiodepressive-like Consequences.

Sellmeijer J, Mathis V, Hugel S, Li XH, Song Q, Chen QY, Barthas F, Lutz PE, Karatas M, Luthi A, Veinante P, Aertsen A, Barrot M, Zhuo M, Yalcin I

J Neurosci. 2018 03 21;38(12):3102-3115

Phenylpyridine-2-ylguanidines and rigid mimetics as novel inhibitors of TNFα overproduction: Beneficial action in models of neuropathic pain and of acute lung inflammation.

Bollenbach M, Salvat E, Daubeuf F, Wagner P, Yalcin I, Humo M, Letellier B, Becker LJ, Bihel F, Bourguignon JJ, Villa P, Obrecht A, Frossard N, Barrot M, Schmitt M

Eur J Med Chem. 2018 Mar 10;147:163-182