Passet M, Kim R, Gachet S, Sigaux F, Chaumeil J, Galland A, Sexton T, Quentin S, Hernandez L, Larcher L, Bergugnat H, Ye T, Karasu N, Caye-Eude A, Heizmann B, Duluc I, Chevallier P, Rousselot P, Huguet F, Leguay TT, Hunault-Berger MM, Pflumio F, Freund JN, Lobry C, Lheritier V, Dombret H, Domon-Dell C, Soulier J, Boissel N, Clappier E

Blood. 2022 Mar 22;:

CDX2 expression in the hematopoietic lineage promotes leukemogenesis via TGFβ inhibition.

Galland A, Gourain V, Habbas K, Güler Y, Martin E, Ebel C, Tavian M, Vallat L, Chenard MP, Mauvieux L, Freund JN, Duluc I, Domon-Dell C

Mol Oncol. 2021 May 6;:

CDX2 regulates ACE expression in blood development and leukemia cells.

El Omar R, Julien E, Biasch K, Guffroy B, Lioure B, Vallat L, Gross I, Domon-Dell C, Lanza F, Gachet C, Negroni M, Freund JN, Tavian M

Blood Adv. 2021 Apr 13;5(7):2012-2016

A Core Response to the CDX2 Homeoprotein During Development and in Pathologies.

Gourain V, Duluc I, Domon-Dell C, Freund JN

Front Genet. 2021 ;12:744165

Fine-tuning and autoregulation of the intestinal determinant and tumor suppressor homeobox gene CDX2 by alternative splicing.

Balbinot C, Vanier M, Armant O, Nair A, Penichon J, Soret C, Martin E, Saandi T, Reimund JM, Deschamps J, Beck F, Domon-Dell C, Gross I, Duluc I, Freund JN

Cell Death Differ.. 2017 Sep;:

Distinct mechanisms for opposite functions of homeoproteins Cdx2 and HoxB7 in double-strand break DNA repair in colon cancer cells.

Soret C, Martin E, Duluc I, Dantzer F, Vanier M, Gross I, Freund JN, Domon-Dell C

Cancer Lett.. 2016 May;374(2):208-15

Extending the functions of the homeotic transcription factor Cdx2 in the digestive system through nontranscriptional activities.

Freund JN, Duluc I, Reimund JM, Gross I, Domon-Dell C

World J Gastroenterol. 2015 Feb 7;21(5):1436-43

Cdx2 homeoprotein inhibits non-homologous end joining in colon cancer but not in leukemia cells.

Renouf B, Soret C, Saandi T, Delalande F, Martin E, Vanier M, Duluc I, Gross I, Freund JN, Domon-Dell C

Nucleic Acids Res. 2012 Apr;40(8):3456-69

CDX2 in congenital gut gastric-type heteroplasia and intestinal-type Meckel diverticula.

Martin E, Vanier M, Tavian M, Guerin E, Domon-Dell C, Duluc I, Gross I, Rowland J, Kim S, Freund JN

Pediatrics. 2010 Sep;126(3):e723-7

Multiple regulatory regions control the complex expression pattern of the mouse Cdx2 homeobox gene.

Benahmed F, Gross I, Gaunt SJ, Beck F, Jehan F, Domon-Dell C, Martin E, Kedinger M, Freund JN, Duluc I

Gastroenterology. 2008 Oct;135(4):1238-1247, 1247.e1-3

Cdx1, a dispensable homeobox gene for gut development with limited effect in intestinal cancer.

Bonhomme C, Calon A, Martin E, Robine S, Neuville A, Kedinger M, Domon-Dell C, Duluc I, Freund JN

Oncogene. 2008 Jul 24;27(32):4497-502

Different effects of the Cdx1 and Cdx2 homeobox genes in a murine model of intestinal inflammation.

Calon A, Gross I, Lhermitte B, Martin E, Beck F, Duclos B, Kedinger M, Duluc I, Domon-Dell C, Freund JN

Gut. 2007 Dec;56(12):1688-95

Multiple-contrast X-ray micro-CT visualization of colon malformations and tumours in situ in living mice.

Choquet P, Calon A, Breton E, Beck F, Domon-Dell C, Freund JN, Constantinesco A

C R Biol. 2007 Nov;330(11):821-7

Frequent rearrangements and amplification of the CDX2 homeobox gene in human sporadic colorectal cancers with chromosomal instability.

Subtil C, Guerin E, Schneider A, Chenard MP, Martin E, Domon-Dell C, Duluc I, Brabletz T, Kedinger M, Duclos B, Gaub MP, Freund JN

Cancer Lett. 2007 Mar 18;247(2):197-203

The microenvironment controls CDX2 homeobox gene expression in colorectal cancer cells.

Benahmed F, Gross I, Guenot D, Jehan F, Martin E, Domon-Dell C, Brabletz T, Kedinger M, Freund JN, Duluc I

Am J Pathol. 2007 Feb;170(2):733-44.

Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies.

Buchet-Poyau K, Courchet J, Le Hir H, Seraphin B, Scoazec JY, Duret L, Domon-Dell C, Freund JN, Billaud M

Nucleic Acids Res. 2007;35(4):1289-300

Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells.

Debruyne PR, Witek M, Gong L, Birbe R, Chervoneva I, Jin T, Domon-Cell C, Palazzo JP, Freund JN, Li P, Pitari GM, Schulz S, Waldman SA

Gastroenterology. 2006 Apr;130(4):1191-206.

Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression.

Brabletz T, Spaderna S, Kolb J, Hlubek F, Faller G, Bruns CJ, Jung A, Nentwich J, Duluc I, Domon-Dell C, Kirchner T, Freund JN

Cancer Res. 2004 Oct 1;64(19):6973-7.

SOX9 is an intestine crypt transcription factor, is regulated by the Wnt pathway, and represses the CDX2 and MUC2 genes.

Blache P, van de Wetering M, Duluc I, Domon C, Berta P, Freund JN, Clevers H, Jay P

J Cell Biol. 2004 Jul 5;166(1):37-47.

Down-regulation of the tumor suppressor PTEN by the tumor necrosis factor-alpha/nuclear factor-kappaB (NF-kappaB)-inducing kinase/NF-kappaB pathway is linked to a default IkappaB-alpha autoregulatory loop.

Kim S, Domon-Dell C, Kang J, Chung DH, Freund JN, Evers BM

J Biol Chem. 2004 Feb 6;279(6):4285-91

Cdx1 homeobox gene during human colon cancer progression.

Domon-Dell C, Schneider A, Moucadel V, Guerin E, Guenot D, Aguillon S, Duluc I, Martin E, Iovanna J, Launay JF, Duclos B, Chenard MP, Meyer C, Oudet P, Kedinger M, Gaub MP, Freund JN

Oncogene. 2003 Sep 11;22(39):7913-21.

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