Garcia-Leon MJ, Liboni C, Mittelheisser V, Bochler L, Follain G, Mouriaux C, Busnelli I, Larnicol A, Colin F, Peralta M, Osmani N, Gensbittel V, Bourdon C, Samaniego R, Pichot A, Paul N, Molitor A, Carapito R, Jandrot-Perrus M, Lefebvre O, Mangin PH, Goetz JG

Nat Commun. 2024 05 13;15(1):3297

The localization, origin, and impact of platelets in the tumor microenvironment are tumor type-dependent.

Le Chapelain O, Jadoui S, Gros A, Barbaria S, Benmeziane K, Ollivier V, Dupont S, Solo Nomenjanahary M, Mavouna S, Rogozarski J, Mawhin MA, Caligiuri G, Delbosc S, Porteu F, Nieswandt B, Mangin PH, Boulaftali Y, Ho-Tin-Noé B

J Exp Clin Cancer Res. 2024 03 16;43(1):84

A macrofluidic model to investigate the intrinsic thrombogenicity of clinically used stents and develop less thrombogenic stents.

Kern AY, Kreinin Y, Charle L, Epshrein M, Korin N, Mangin PH

Heliyon. 2024 03 15;10(5):e26550

Mice expressing nonpolymerizable fibrinogen have reduced arterial and venous thrombosis with preserved hemostasis.

Hur WS, Kawano T, Mwiza JMN, Paul DS, Lee RH, Clark EG, Bouck EG, Dutta A, Cai C, Baker SR, Guthold M, Mackman N, Mangin PH, Wolberg AS, Bergmeier W, Flick MJ

Blood. 2023 10 13;:

Biochemical and functional characteristics of stored (double-dose) buffy-coat platelet concentrates treated with amotosalen and a prototype UVA light-emitting diode illuminator.

Brouard N, Pissenem-Rudwill F, Mouriaux C, Haas D, Galvanin A, Kientz D, Mangin PH, Isola H, Hechler B

Transfusion. 2023 08 24;:

Amplified inhibition of atherosclerotic plaque-induced platelet activation by glenzocimab with dual antiplatelet therapy.

Alenazy FO, Harbi MH, Kavanagh DP, Price J, Brady P, Hargreaves O, Harrison P, Slater A, Tiwari A, Nicolson PLR, Connolly DL, Kirchhof P, Kalia N, Jandrot-Perrus M, Mangin PH, Watson SP, Thomas MR

J Thromb Haemost. 2023 08 2;:

GPVI interplay with fibrin(ogen) in thrombosis.

Mangin PH, Gardiner EE, Ariëns RAS, Jandrot-Perrus M

J Thromb Haemost. 2023 03 27;:

Comparison of three antithrombotic strategies for emergent carotid stenting during stroke thrombectomy: a multicenter study.

Pop R, Burel J, Finitsis SN, Papagiannaki C, Severac F, Mangin PH, Mihoc D, Leonard-Lorant I, Gheoca R, Wolff V, Chibbaro S, Sibon I, Richard S, Beaujeux R, Marnat G, Gory B

J Neurointerv Surg. 2023 02 9;:

The relative importance of platelet integrins in hemostasis, thrombosis and beyond.

Janus-Bell E, Mangin PH

Haematologica. 2023 01 26;:

Discriminating young platelets on human leukocyte antigen-I expression highlights their extremely high reactivity potential.

Angénieux C, Couvidou A, Brouard N, Eckly A, Dupuis A, Mangin PH, Maître B

Res Pract Thromb Haemost. 2023 01;7(1):100006

Marginal zone B cells are responsible for the production of alloantibodies following platelet transfusion in mice.

Couvidou A, Angénieux C, Ruch L, Mangin PH, Gachet C, Maître B

Blood Adv. 2022 12 9;:

Platelet dysfunction and thrombus instability in flow conditions in patients with severe COVID-19.

Tacquard C, Mouriaux C, Delabranche X, Bourdon C, Eckly A, Magnenat S, Sattler L, Gachet C, Mertes PM, Hechler B, Mangin PH

Thromb Res. 2022 11 8;:

Loss of α4A- and β1-tubulin leads to severe platelet spherocytosis and strongly impairs hemostasis in mice.

Kimmerlin Q, Moog S, Yakusheva AA, Eckly AE, Freund M, Závodszky G, Knapp Y, Mangin PH, Lanza F

Blood. 2022 08 26;:

Traumatic vessel injuries initiating hemostasis generate high shear conditions.

Yakusheva AA, Butov KR, Bykov GA, Závodszky G, Eckly AE, Ataullakhanov FI, Gachet C, Panteleev MA, Mangin PH

Blood Adv. 2022 06 21;:

Conservative versus aggressive antiplatelet strategy for emergent carotid stenting during stroke thrombectomy.

Pop R, Severac F, Hasiu A, Mihoc D, Mangin PH, Chibbaro S, Simu M, Tudor R, Gheoca R, Quenardelle V, Wolff V, Beaujeux R

Interv Neuroradiol. 2022 Mar 7;:15910199221083112

The Effects of Micro-vessel Curvature Induced Elongational Flows on Platelet Adhesion.

Spieker CJ, Závodszky G, Mouriaux C, van der Kolk M, Gachet C, Mangin PH, Hoekstra AG

Ann Biomed Eng. 2021 Oct 19;:

Characterization of the role of integrin α5β1 in platelet function, hemostasis and experimental thrombosis.

Janus-Bell E, Yakusheva A, Scandola C, Receveur N, Muhammad-Usman A, Mouriaux C, Bourdon C, Loubière C, Eckly A, Senis YA, Panteleev MA, Gachet C, Mangin PH

Thromb Haemost. 2021 Oct 1;:

Respective roles of Glycoprotein VI and FcγRIIA in the regulation of αIIbβ3-mediated platelet activation to fibrinogen, thrombus buildup, and stability.

Ahmed MU, Receveur N, Janus-Bell E, Mouriaux C, Gachet C, Jandrot-Perrus M, Hechler B, Gardiner EE, Mangin PH

Res Pract Thromb Haemost. 2021 Jul;5(5):e12551

Postprocedural Antiplatelet Treatment after Emergent Carotid Stenting in Tandem Lesions Stroke: Impact on Stent Patency beyond Day 1.

Pop R, Hasiu A, Mangin PH, Severac F, Mihoc D, Nistoran D, Manisor M, Simu M, Chibbaro S, Gheoca R, Quenardelle V, Rouyer O, Wolff V, Beaujeux R

AJNR Am J Neuroradiol. 2021 Feb 18;:

Wall shear rates in human and mouse arteries: Standardization of hemodynamics for in vitro blood flow assays: Communication from the ISTH SSC subcommittee on biorheology.

Panteleev MA, Korin N, Reesink KD, Bark DL, Cosemans JMEM, Gardiner EE, Mangin PH

J Thromb Haemost. 2021 Feb;19(2):588-595

Glenzocimab does not impact glycoprotein VI-dependent inflammatory haemostasis.

Jadoui S, Le Chapelain O, Ollivier V, Mostefa-Kara A, Di Meglio L, Dupont S, Gros A, Nomenjanahary MS, Desilles JP, Mazighi M, Nieswandt B, Loyau S, Jandrot-Perrus M, Mangin PH, Ho-Tin-Noé B

Haematologica. 2020 Dec 30;Online ahead of print:

Liquid flow and control without solid walls.

Dunne P, Adachi T, Dev AA, Sorrenti A, Giacchetti L, Bonnin A, Bourdon C, Mangin PH, Coey JMD, Doudin B, Hermans TM

Nature. 2020 05;581(7806):58-62

The basement membrane protein nidogen-1 supports platelet adhesion and activation.

Lakshmanan HHS, Melrose AR, Sepp AI, Mitrugno A, Ngo ATP, Khader A, Thompson R, Sallee D, Pang J, Mangin PH, Jandrot-Perrus M, Aslan JE, McCarty OJT

Platelets. 2020 Apr 1;:1-5

In vitro flow based systems to study platelet function and thrombus formation: Recommendations for standardization: Communication from the SSC on Biorheology of the ISTH.

Mangin PH, Gardiner EE, Nesbitt WS, Kerrigan SW, Korin N, Lam WA, Panteleev MA,

J Thromb Haemost. 2020 03;18(3):748-752

Functional properties of human platelets derived in vitro from CD34 cells.

Do Sacramento V, Mallo L, Freund M, Eckly A, Hechler B, Mangin P, Lanza F, Gachet C, Strassel C

Sci Rep. 2020 Jan 22;10(1):914

Shear rate gradients promote a bi-phasic thrombus formation on weak adhesive proteins, such as fibrinogen in a VWF-dependent manner.

Receveur N, Nechipurenko D, Knapp Y, Yakusheva A, Maurer E, Denis CV, Lanza F, Panteleev M, Gachet C, Mangin PH

Haematologica. 2019 Nov 14;105(10):2471-2483

Tenascin-C increases lung metastasis by impacting blood vessel invasions.

Sun Z, Velázquez-Quesada I, Murdamoothoo D, Ahowesso C, Yilmaz A, Spenlé C, Averous G, Erne W, Oberndorfer F, Oszwald A, Kain R, Bourdon C, Mangin P, Deligne C, Midwood K, Abou-Faycal C, Lefebvre O, Klein A, van der Heyden M, Chenard MP, Christofori G, Mathelin C, Loustau T, Hussenet T, Orend G

Matrix Biol.. 2019 Jul 6;:

Aryl hydrocarbon receptor-dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets.

Strassel C, Brouard N, Mallo L, Receveur N, Mangin P, Eckly A, Bieche I, Tarte K, Gachet C, Lanza F

Blood. 2016 05 5;127(18):2231-40