EN DE

Dr DEVYS Didier

Fiche personne

coordonnées

IGBMC
1 rue Laurent Fries
BP 10142
67404 ILLKIRCH

devys@igbmc.fr

Territoire

Alsace

Statut

Chercheur

affiliation

IGBMC - Institut de génétique et de biologie moléculaire et cellulaire (IGBMC)

équipes/plateformes

Equipe Equipe "Biologie du développement et cellules souches / Modifications de la chromatine et régulation de la transcription des gènes lors de la différentiation cellulaire"

Recherche

Publications

De novo variants in ATXN7L3 lead to developmental delay, hypotonia and distinctive facial features.

Harel T, Spicher C, Scheer E, Buchan JG, Cech J, Folland C, Frey T, Holtz AM, Innes AM, Keren B, Macken WL, Marcelis C, Otten CE, Paolucci SA, Petit F, Pfundt R, Pitceathly RDS, Rauch A, Ravenscroft G, Sanchev R, Steindl K, Tammer F, Tyndall A, Devys D, Vincent SD, Elpeleg O, Tora L

Brain. 2024 05 16;:

Transcription factor IID parks and drives preinitiation complexes at sharp or broad promoters.

Bernardini A, Hollinger C, Willgenss D, Müller F, Devys D, Tora L

Trends Biochem Sci. 2023 08 11;:

SAGA-Dependent Histone H2Bub1 Deubiquitination Is Essential for Cellular Ubiquitin Balance during Embryonic Development.

El-Saafin F, Devys D, Johnsen SA, Vincent SD, Tora L

Int J Mol Sci. 2022 07 5;23(13):

The related coactivator complexes SAGA and ATAC control embryonic stem cell self-renewal through acetyltransferase-independent mechanisms.

Fischer V, Plassard D, Ye T, Reina-San-Martin B, Stierle M, Tora L, Devys D

Cell Rep. 2021 Aug 24;36(8):109598

Architectural Mediator subunits are differentially essential for global transcription in Saccharomyces cerevisiae.

Tourigny JP, Schumacher K, Saleh MM, Devys D, Zentner GE

Genetics. 2021 Mar 31;217(3):

Histone H2Bub1 deubiquitylation is essential for mouse development, but does not regulate global RNA polymerase II transcription.

Wang F, El-Saafin F, Ye T, Stierle M, Negroni L, Durik M, Fischer V, Devys D, Vincent SD, Tora L

Cell Death Differ. 2021 Mar 17;:

What do the structures of GCN5-containing complexes teach us about their function?

Helmlinger D, Papai G, Devys D, Tora L

Biochim Biophys Acta Gene Regul Mech. 2020 Jul 30;:194614

Saccharomyces cerevisiae Metabolic Labeling with 4-thiouracil and the Quantification of Newly Synthesized mRNA As a Proxy for RNA Polymerase II Activity.

Baptista T, Devys D

J Vis Exp. 2018 Oct 22;(140):

Global role for coactivator complexes in RNA polymerase II transcription.

Fischer V, Schumacher K, Tora L, Devys D

Transcription. 2018 Oct 9;:1-8

Mediator is essential for small nuclear and nucleolar RNA transcription in yeast.

Tourigny JP, Saleh MM, Schumacher K, Devys D, Zentner GE

Mol. Cell. Biol.. 2018 Oct 1;:

SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Baptista T, Grünberg S, Minoungou N, Koster MJE, Timmers HTM, Hahn S, Devys D, Tora L

Mol. Cell. 2018 Jun 21;70(6):1163-1164

Morphological features in juvenile Huntington disease associated with cerebellar atrophy - magnetic resonance imaging morphometric analysis.

Hedjoudje A, Nicolas G, Goldenberg A, Vanhulle C, Dumant-Forrest C, Deverrière G, Treguier P, Michelet I, Guyant-Maréchal L, Devys D, Gerardin E, Dacher JN, Vivier PH

Pediatr Radiol. 2018 Jun 20;:

Homozygous TAF8 mutation in a patient with intellectual disability results in undetectable TAF8 protein, but preserved RNA Polymerase II transcription.

El-Saafin F, Curry C, Ye T, Garnier JM, Kolb-Cheynel I, Stierle M, Downer NL, Dixon MP, Negroni L, Berger I, Thomas T, Voss AK, Dobyns W, Devys D, Tora L

Hum. Mol. Genet.. 2018 Apr 10;:

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.

Gupta K, Watson AA, Baptista T, Scheer E, Chambers AL, Koehler C, Zou J, Obong-Ebong I, Kandiah E, Temblador A, Round A, Forest E, Man P, Bieniossek C, Laue ED, Lemke EA, Rappsilber J, Robinson CV, Devys D, Tora L, Berger I

Elife. 2017 Nov 7;6:

SAGA Is a General Cofactor for RNA Polymerase II Transcription.

Baptista T, Grünberg S, Minoungou N, Koster MJE, Timmers HTM, Hahn S, Devys D, Tora L

Mol. Cell. 2017 Sep;:

Transcription of Nearly All Yeast RNA Polymerase II-Transcribed Genes Is Dependent on Transcription Factor TFIID.

Warfield L, Ramachandran S, Baptista T, Devys D, Tora L, Hahn S

Mol. Cell. 2017 Sep;:

Deciphering the causes of sporadic late-onset cerebellar ataxias: a prospective study with implications for diagnostic work.

Gebus O, Montaut S, Monga B, Wirth T, Cheraud C, Alves Do Rego C, Zinchenko I, Carré G, Hamdaoui M, Hautecloque G, Nguyen-Them L, Lannes B, Chanson JB, Lagha-Boukbiza O, Fleury MC, Devys D, Nicolas G, Rudolf G, Bereau M, Mallaret M, Renaud M, Acquaviva C, Koenig M, Koob M, Kremer S, Namer IJ, Cazeneuve C, Echaniz-Laguna A, Tranchant C, Anheim M

J. Neurol.. 2017 May;:

Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes.

Helmlinger D, Hardy S, Sasorith S, Klein F, Robert F, Weber C, Miguet L, Potier N, Van-Dorsselaer A, Wurtz JM, Mandel JL, Tora L, Devys D

Hum. Mol. Genet.. 2004 Jun;13(12):1257-65