Inter-clinician variability in making dosimetric decisions in pediatric treatment: a balance between efficacy and late effects.
Fiche publication
Date publication
novembre 2009
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BERNIER-CHASTAGNER Valérie, Dr QUETIN Philippe
Tous les auteurs :
Padovani L, Huchet A, Claude L, Bernier V, Quetin P, Mahe M, Laprie A, Kerr C, Bondiau PY, Delarue A, Coze C, Gibon D, Barteau C, Maire JP, Carrie C, Muracciole X
Lien Pubmed
Résumé
PURPOSE: To investigate variability of clinical target volume (CTV) delineation and deviations according to doses delivered in normal tissue for abdominal tumor irradiation in children. MATERIAL AND METHODS: For a case of nephroblastoma six French pediatric radiation oncologists outlined post-operative CTV, on the same dosimetric CT scan according to the International Society for Pediatric Oncology 2001 protocol. On a reference CTV and organs at risk (OAR), we performed dosimetric planning with the constraints as 25.2 Gy for CTV, V(20 max) to 50% for liver, V(12)
Référence
Radiother Oncol. 2009 Nov;93(2):372-6