The role of the FDG-PET in the evaluation of efficacy of radiofrequency treatment of metastases
Fiche publication
Date publication
septembre 2009
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BLAGOSKLONOV Oleg, Pr BOULAHDOUR Hatem
Tous les auteurs :
Ungureanu CM, Kastler B, Angoue O, Blagosklonov O, Zsigmond R, Boulahdour H
Lien Pubmed
Résumé
Objectives. - Methods such as MRI and CT usually utilized in the assessment of the radiofrequency (RF) efficacy proved to be insufficient in the early detection of the residual tumors after RF treatment. In this study, we evaluated the effectiveness of utilizing the PET-CT in the follow-up of the RF treated patients. Methods. - PET-CT was performed before and after five RF treatments (three patients). Absence of focally increased FDG uptake was considered complete efficacy, while the presence of focally increased FDG uptake was considered incomplete efficacy. The efficacy was estimated on the PET-CT performed in the same day to three months after the RF treatment. Every RF administration was followed by at least two PET-CT exams. We used radiological evaluation as a control method. Results. - Complete efficacy was found for three of the five RF treatments and incomplete efficacy in two cases. The disease evolution confirmed the results obtained through PET-CT in 100% of the cases studied. Conclusion. - This preliminary study showed that the PET-CT has the potential of evaluating the efficacy of the RF treatment. Our findings showed that the PET-CT may very early evidence the presence of residual tumors. (C) 2009 Elsevier Masson SAS. All rights reserved.
Référence
Med Nucl-imag Fonct Metab. 2009 Sep;33(9):553-7